Fig. 1
From: Plumbagin attenuates Bleomycin-induced lung fibrosis in mice
Examinations of fibrotic alterations in the mouse lungs from all of the experimental groups. A Histological examination of lung tissue was conducted by H&E staining, indicating the infiltration of immune cells and structural distortion. B Masson’s trichrome staining indicates the interstitial deposition of collagen (blue color) and the disruption of alveolar spaces. C Percent of the fibrotic area in the lung was quantitated by ImageJ software in trichrome staining sections. n = 3, in each group. D Evaluation of collagen contents was conducted by enzymatic assessment of hydroxyproline and values displayed per mg lung tissue. n = 10, in each group. Data are expressed as mean ± SD. ***p < 0.001, No drawing the comparative rectangle, and corresponding p-value means no significance