Table 1 Patient characteristics, by IgRT modality and history

Age (years), median [IQR]

60 [37, 67]

54

59 [48, 67]

242

64 [52, 68]

65

57 [45, 64]

151

0.43

0.13

0.94

Age at diagnosis (years), median [IQR]

38 [18, 60]

54

45 [27, 60]

239

54 [40, 64]

63

40 [23, 54]

150

0.23

0.003

0.79

Gender, n (%)

 Female

24 (44.4%)

54

151 (63.0%)

240

35 (54.7%)

64

94 (62.7%)

150

0.01

0.27

0.02

 Male

30 (55.6%)

89 (37.1%)

29 (45.3%)

56 (37.3%)

Weight (kg)

74.2 ± 15.1

47

75.8 ± 17.4

216

80.5 ± 15.3

53

73.8 ± 16.3

138

0.56

0.05

0.89

Underlying condition, n (%)

 CVID

21 (51.2%)

41

85 (45.0%)

189

20 (41.7%)

48

56 (45.5%)

123

0.35

0.32

0.23

 IgG Sub

9 (22.0%)

48 (25.4%)

10 (20.8%)

35 (28.5%)

 DGS

2 (4.9%)

8 (4.2%)

4 (8.3%)

3 (2.4)

 SID

1 (2.4%)

22 (11.6%)

7 (14.6%)

14 (11.4%)

 Other*

8 (19.5%)

26 (13.8%)

7 (14.6%)

15 (12.2%)

Years since diagnosis, n (%)

  < 2 years

3 (5.6%)

54

16 (6.7%)

239

10 (15.9%)

63

5 (3.3%)

150

0.24

 < 0.001

0.74

 2–9 years

20 (37.0%)

116 (48.5%)

41 (65.1%)

60 (40.0%)

  ≥ 10 years

31 (57.4%)

107 (44.8%)

12 (19.1%)

85 (56.7%)

Time on IgG, n (%)

  < 1 year

1 (1.9%)

54

11 (4.6%)

242

7 (10.8%)

65

3 (2.0%)

151

0.6

 < 0.001

0.82

 1–2 years

5 (9.3%)

35 (14.5%)

10 (15.4%)

21 (13.9%)

 2–3 years

7 (13.0%)

31 (12.8%)

13 (20.0%)

13 (8.6%)

 4–6 years

11 (20.4%)

55 (22.7%)

24 (36.9%)

24 (15.9%)

  ≥ 6 years

30 (55.6%)

110 (45.5%)

11 (16.9%)

90 (59.6%)

Current treatment experience, n (%)

  < 2 years

4 (8.5%)

47

35 (14.7%)

238

12 (18.5%)

65

20 (13.5%)

148

0.02

 < 0.001

0.23

 2–9 years

23 (48.9%)

148 (62.2%)

46 (70.8%)

84 (56.8%)

 ≥ 10 years

20 (42.6%)

55 (23.1%)

7 (10.8%)

44 (29.7%)

Antibiotics before IgG, n (%)

 No

29 (70.7%)

41

157 (73.7%)

213

48 (81.4%)

59

94 (71.2%)

132

0.69

0.21

0.95

 Yes

12 (29.3%)

56 (26.3%)

11 (18.6%)

38 (28.8%)

Antibiotics since starting IgG, n (%)

 No

9 (21.4%)

42

91 (39.6%)

230

29 (46.0%)

63

53 (37.1%)

143

0.03

0.01

0.06

 Yes

33 (78.6%)

139 (60.4%)

34 (54.0%)

90 (62.9%)

Missed work/school due to treatment regimen, n (%)

 No

36 (66.7%)

54

221 (91.7%)

2

63 (96.7%)

65

134 (89.3%)

150

 < 0.001

 < 0.001

 < 0.001

 Yes

18 (33.3%)

20 (8.3%)

2 (3.1%)

16 (10.7%)