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Table 2 IgRT infusion characteristics: IVIg vs. SCIg

From: Immunoglobulin replacement therapy in patients with immunodeficiencies: impact of infusion method on patient-reported outcomes

Infusion characteristics

IVIg cohort (n = 54)

SCIg cohort (n = 242)

p-value

Summary

n

Summary

n

Frequency of treatment, n (%)

   

 Every day

0 (0.0%)

29

2 (0.9%)

219

 < 0.001

 Two per week

0 (0.0%)

 

15 (6.9%)

  

 Three per week

0 (0.0%)

 

10 (4.6%)

  

 Weekly

1 (3.5%)

 

163 (74.4%)

  

 Every 2 weeks

1 (3.5%)

 

29 (13.2%)

  

 Every 3 weeks

5 (17.2%)

 

0 (0.0%)

  

 Every 4 weeks

22 (75.9%)

 

0 (0.0%)

  

Travel time (mins)* (median [IQR])

40 [30, 90]

27

60 [30, 75]

195

N/A

Trips to hospital/pharmacy to pick up SCIg supplies per month, n (%)

  

  < 1

N/A

N/A

119 (58.1%)

205

N/A

 1

  

80 (39.0%)

  

 2

  

2 (1.0%)

  

 3

  

1 (0.5%)

  

 4

  

2 (1.0%)

  

  > 4

  

1 (0.5%)

  

Location of infusions, n (%)

   

 Hospital

27 (96.4%)

28

N/A

N/A

N/A

 Home

1 (3.6%)

    

Infusion preparation time (mins) (median [IQR])

30 [15, 30]

27

15 [10, 20]

207

 < 0.001

Actual infusion time (mins) (median [IQR])

165 [126, 255]

28

60 [40, 90]

207

 < 0.001

Post-infusion clean up time (mins) (median [IQR])

15 [6, 20]

27

5 [5, 10]

201

0.005

  1. Data were compared using a Mann-Whitney test. *Travel time to infusion center for IVIg respondents, travel time to the pharmacy/hospital for SCIg respondents. Significant p-values are highlighted in bold. IgRT immunoglobulin replacement therapy, IQR interquartile range, IVIg intravenous immunoglobulin, mins minutes, N/A not applicable, SCIg subcutaneous immunoglobulin