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Table 3 Characteristics of respondent training for SCIg self-infusion by IgRT history

From: Immunoglobulin replacement therapy in patients with immunodeficiencies: impact of infusion method on patient-reported outcomes

SCIg training characteristics

SCIg naïve subgroup (n = 65)

SCIg switch subgroup (n = 151)

p-value

Summary

n

Summary

n

 

Ease of SCIg training, n (%)

 Very difficult

1 (1.6%)

63

4 (3.0%)

134

0.88

 Difficult

6 (9.5%)

 

8 (6.0%)

  

 Neither

8 (12.7%)

 

21 (15.7%)

  

 Easy

24 (38.1%)

 

52 (38.8%)

  

 Very easy

24 (38.1%)

 

49 (36.6%)

  

Number of SCIg training sessions, n (%)

     

 1

33 (52.4%)

63

68 (50.8%)

134

0.9

 2

16 (25.4%)

 

38 (28.4%)

  

 3

9 (14.3%)

 

17 (12.7%)

  

 4

3 (4.8%)

 

4 (3.0%)

  

 5

1 (1.6%)

 

1 (0.8%)

  

 > 5

1 (1.6%)

 

6 (4.5%)

  

SCIg training locations, n (%)

    

 Doctors’ office

0 (0.0%)

63

5 (3.7%)

134

0.36

 Home

19 (30.2%)

 

44 (32.8%)

  

 Hospital

39 (61.9%)

 

80 (59.7%)

  

 Infusion center

2 (3.2%)

 

3 (2.2%)

  

 Other*

3 (4.8%)

 

2 (1.5%)

  

Type of SCIg trainer, n (%)

     

 Doctor’s office staff

4 (6.5%)

62

13 (9.8%)

133

0.7

 Hospital nurse

39 (62.9%)

 

76 (57.1%)

  

 Hizentra CARE nurse

19 (30.7%)

 

41 (30.8%)

  

 Other†

0 (0.0%)

 

3 (2.3%)

  

Trainer knowledge, n (%)

     

 Very naïve

0 (0.0%)

63

0 (0.0%)

132

0.33

 Naive

2 (3.2%)

 

2 (1.5%)

  

 Neither

0 (0.0%

 

1 (0.8%)

  

 Knowledgeable

3 (4.8%)

 

14 (10.6%)

  

 Very knowledgeable

58 (92.1%)

 

115 (87.1%)

  

Trainer competency, n (%)

     

 Very incompetent

0 (0.0%)

62

1 (0.8%)

133

0.09

 Incompetent

1 (1.6%)

 

2 (1.5%)

  

 Neither

0 (0.0%)

 

1 (0.8%)

  

 Competent

2 (0.0%)

 

13 (9.8%)

  

 Very competent

59 (95.2%)

 

116 (87.2%)

  

Self-administration confidence, n (%)

     

 Very uncertain

0 (0.0%)

63

1 (0.8%)

133

0.41

 Uncertain

5 (7.9%)

 

6 (4.5%)

  

 Neither

2 (3.2%)

 

11 (8.3%)

  

 Confident

20 (31.8%)

 

48 (36.1%)

  

 Very confident

36 (57.1%)

 

67 (50.4%)

  

Training

     

satisfaction, n (%)

     

 Very dissatisfied

0 (0.0%)

63

0 (0.0%)

133

0.06

 Dissatisfied

0 (0.0%)

 

3 (2.3%)

  

 Neither

1 (1.6%)

 

3 (2.3%)

  

 Satisfied

7 (11.1%)

 

26 (19.6%)

  

 Very satisfied

55 (87.3%)

 

101 (75.9%)

  

Perceived barriers to training, n (%)

     

 No

57 (100%)

57

120 (99.2%)

121

1

 Yes

0 (0.0%)

 

1 (0.8%)

  

Length of training (hours) (median [IQR])

2 [1, 2]

60

1.5 [1, 2]

127

0.52

Greatest training concern‡, n (%)

     

 Drawing the drug

6 (9.5%)

63

19 (14.4%)

132

0.82

 Inserting the needle

27 (42.9%)

 

58 (43.9%)

  

 Operating the pump

2 (3.2%)

 

2 (1.5%)

  

 Priming the tube

3 (4.8%)

 

7 (5.3%)

  

 Other

1 (1.6%)

 

1 (0.8%)

  

 No concerns

24 (38.1%)

 

45 (34.1%)

  
  1. Data were compared using a Mann-Whitney test (ease of SCIg training, number of SCIg training sessions) or Fisher’s exact test (SCIg training location, type of SCIg trainer). Significant p values are in bold. *Other training locations: Institut de rescherches Clinique de Montreal (n = 4) and a local community services centre (n = 1). †Other trainers: home health/specialty pharmacy staff (n = 1), one PATH nurse (n = 1), and ProCare (n = 1). ‡Other concerns: tip-to-tip transfer (n = 2) and applying needles to tubing (n = 2). IgRT immunoglobulin replacement therapy, IQR interquartile range, SCIg subcutaneous immunoglobulin
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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