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Table 2 Immunologic lab data at the time of IEI diagnosis

From: Diversity of malignancies in patients with different types of inborn errors of immunity

Parameters

HL (n = 19)

NHL (n = 36)

Leukemia (n = 9)

Solid tumor (n = 15)

p value*

Leukocyte/µl, median (IQR)

7600 (6565–9900)

6900 (3800–9630)

4400 (3100–13,340)

7100 (4290–12,600)

0.83

Lymphocyte/µl, median (IQR)

2721 (2412–4054)

2184 (1329–3651)

3080 (2137–26,904)

772 (510–2612)

0.05*

Neutrophils/µl, median (IQR)

3984 (2809–5527)

3608 (2933–7121)

1800 (691–73,402)

3900 (2940–5428)

0.85

Absolute T cells/µl, median (IQR)

2217 (1448–2856)

1519 (763–1936)

2022 (1167–2791)

464 (355–665)

0.09

Absolute T4 cells/µl, median (IQR)

552 (265–957)

325 (134–989)

606 (457–864)

238 (230–340)

0.14

Absolute T8 cells/µl, median (IQR)

2217 (1448–2856)

1519 (763–1936)

2022 (1167–2791)

464 (355–665)

0.08

Absolute NK cells/µl, median (IQR)

118 (102–129)

231 (80–693)

313 (125–452)

170 (68–219)

0.26

Absolute B cells/µl, median (IQR)

134 (46–295)

183 (68–359)

225 (123–540)

38 (20–110)

0.07

Serum IgG mg/dl, median (IQR)

587 (339–993)

300 (71–640)

130 (13.7–517)

400 (46–1360)

0.93

Serum IgA mg/dl, median (IQR)

28 (3.5–84)

8 (2–40)

16.5 (3.5–44)

16 (4–37.5)

0.92

Serum IgM mg/dl, median (IQR)

49 (15–123)

41 (20–117)

24 (8.5–64)

67 (22–122)

0.65

Serum IgE IU/ml, median (IQR)

3 (0.07–14)

25 (0.9–226)

1 (0.5–1.5)

10 (4.8–11,705)

0.35

  1. *p-value calculated to indicate significant differences between hematologic and solid tumors