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Table 1 Baseline characteristics

From: Impact of antigen avoidance test for fibrotic hypersensitivity pneumonitis in stable phase

Subjects

Positive antigen avoidance test (n = 17)

Negative antigen avoidance test (n = 23)

p-value

Age (years)

73 (69–77)

74 (67–77)

0.94

Sex (M/F), n

7/ 10

13/ 9

0.34

Smoking history (Yes), n

5

13

0.12

Surgical lung biopsy, n

5

9

0.74

Cryobiopsy, n

13

17

1.00

CT performed after the antigen avoidance test, n

15

18

0.68

White blood cell (/μL)

6100 (5750–6910)

5630 (4990–7170)

0.71

C-reactive protein (mg/dL)

0.10 (0.06–0.15)

0.10 (0.05–0.28)

0.06

Serum Krebs von den Lungen-6 (U/mL)

1627 (821–2906)

1637 (1015–2509)

0.62

FVC (L)

1.92 (1.62–2.49)

2.12 (1.87–2.76)

0.26

FVC %pred (%)

80 (64–90)

78 (67–94)

0.91

PaO2 (Torr)

78.5 (68.9–85.6)

82.9 (75.0–91.8)

0.89

A-aDO2 (Torr)

19.0 (13.5–25.9)

18.0 (9.1–22.5)

0.19

BAL lymphocytes (%)

43 (24–64)

25 (17–45)

0.27

Anti-bird IgG antibodies (mgA/L)

14 (10–19)

12 (8–14)

0.13

Anti-Tricosporon asahii IgG antibody (CAI)

0.01 (0–0.04)

0.00 (0–0.05)

0.48

Airway-centered fibrosis, n

11

18

0.48

Lymphocyte-predominant bronchiolitis, n

11

15

1.00

Poorly formed granulomas, n

12

13

0.51

Fibroblastic foci, n

9

19

0.08

Organizing pneumonia, n

13

19

0.70

Prednisolone, n

0

1

 

Immunosuppressant, n

0

1

 

Anti-fibrotic agents, n

0

1

 
  1. Data are presented as median (IQR) or n (%). The reference ranges of anti-pigeon and anti-parrot IgG antibodies are 0–24.0 mgA/L and 0–14.0 mgA/L respectively
  2. FVC: forced vital capacity; %pred: % predicted; PaO2: partial pressure of arterial oxygen; BAL: bronchoalveolar lavage; CAI: corrected absorbance index