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Table 2 Comparison of respiratory function test results in patients with asthma before and after the intervention

From: Immunomodulatory effects of probiotic supplementation in patients with asthma: a randomized, double-blind, placebo-controlled trial

Variables

Probiotic group (n = 17)

Placebo group (n = 18)

Cohen’s d (95% CI)

p

FEV1 (L)

 Baseline

2.5 ± 0.66

2.41 ± 0.6

0.14 (−0.52 to 0.80)

0.674t

 2nd consultation

2.7 ± 0.66

2.40 ± 0.64

0.46 (−0.22 to 1.12)

0.135t

 Cohen’s d (95% CI)

−0.30 (−0.98 to 0.38)

0.01 (−0.65 to 0.68)

  

 p

0.0039tp

0.577tp

  

FVC (L)

 Baseline

3.4 ± 0.69

3.2 ± 0.65

0.29 (−0.37 to 0.96)

0.449t

 2nd consultation

3.6 ± 0.57

3.3 ± 0.68

0.47 (−0.21 to 1.14)

0.143t

 Cohen’s d (95% CI)

−0.31 (−0.98 to 0.37)

−0.15 (−0.80 to 0.51)

  

 p

0.0007tp

0.150tp

  

FEV1/FVC (%)

 Baseline

72 ± 7

73 ± 17

−0.07 (−0.74 to 0.59)

0.241w

 2nd consultation

74 ± 11

71 ± 17

0.21 (−0.54 to 0.77)

0.285w

 Cohen’s d (95% CI)

−0.21 (−0.89 to 0.46)

0.12 (−0.54 to 0.77)

  

 p

0.463wp

0.202wp

  
  1. T Student’s t and W the Wilcoxon Mann-Whitney tests for independent samples and Tp Student’s t and Wp the Wilcoxon tests for paired samples.
  2. FEV1 forced expiratory volume in one second, FVC forced vital capacity