Table 1 Comparison of demographic and clinical parameters between the 3 study groups
From: Cow’s milk allergy skin tests: fresh milk, commercial extracts, or both?
Total (n = 388) | Allergic—total (Group A) (N = 227) | (B) Not allergic by OFC (Group B) (n = 161) | ||
|---|---|---|---|---|
Allergic by OFC (A.1) (n = 30) | Allergic by SPT (A.2) (n = 197) | |||
Male sex, n (%) | 215 (55.4) | 139a (61) | 76b (47.5) | |
20a,b (64.5) | 119a (60.4) | |||
Age at first exposure, (months) mean ± SD (95% CI) | 3.32 ± 3.29 (2.93–3.7) | 3.44 ± 3.38a (2.93–3.95) | 3.12 ± 3.16a (2.53–3.72) | |
3.69 ± 2.93a (2.45–4.93) | 3.4 ± 3.45a (2.84–3.96) | |||
Age at first reaction (months), mean ± SD (95% CI) | 5.04 ± 2.89 (4.74–5.35) | 5.03 ± 3.06a (4.61–5.45) | 5.07 ± 2.64a (4.63–5.5) | |
4.47 ± 2.51a (3.51–5.42) | 5.1 ± 3.14a (4.64–5.56) | |||
Age at last SPT (years), mean ± SD (95% CI) | 4.43 ± 3.06 (4.09–4.76) | 5.27 ± 3.39a (4.76–5.78) | 3.46 ± 2.29b,§ (3.09–3.83) | |
4.82 ± 3.92a,§ (3.3–6.34) | 5.36 ± 3.28a (4.82–5.9) | |||
Asthma, n (%) | 82 (21.13) | 68a (30) | 14b,§ (8.75) | |
7a,§ (22.58) | 61a (31.12) | |||
Atopic dermatitis, n (%) | 68 (17.52) | 41a (18.1) | 27a (16.9) | |
6a (19.35) | 35a (17.7) | |||
Other food allergy, n (%) | 78 (20.1) | 55a (24.2) | 23b (14.4) | |
5a,b (16.1) | 50a (25.5) | |||
Family atopic background, n (%) | 185 (52.4) | 117a (54.4) | 68a (49.3) | |
17a (58.6) | 100a (53.8) | |||
Symptoms during the first reaction, n (%) | ||||
Rash | 335 (86.3) | 203a (91) | 132a (84.6) | |
27a (87.1) | 176a (91.7) | |||
Breathing difficulties | 55 (14.5) | 48a (21.5) | 7b (4.5) | |
4a,b (12.9) | 44a (22.9) | |||
Vomiting | 212 (55.9) | 132a (59.2) | 80a (55.9) | |
18a (58.1) | 114a (59.4) | |||
Eosinophils at diagnosis mean ± SD (95% CI) | 487.74 ± 520.66 (435.57–539.91) | 546.23 ± 595.12a (468.57–623.89) | 402.8 ± 373.72b (343.89–461.72) | |
431.29 ± 335.1a,b (308.37–554.21) | 564.31 ± 624.96a (476.5–652.13) | |||