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  1. Asthma is one of the most common chronic diseases in childhood and is generally characterized by exercise induced bronchoconstriction (EIB). Assessing EIB is time consuming and expensive as it requires a fully...

    Authors: M. R. van der Kamp, J. M. M. Driessen, M. P. van der Schee, B. J. Thio and F. H. C. de Jongh

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:121

    Content type: Research

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  2. The hygiene hypothesis posits that microbial exposure reduces risk of asthma and other respiratory-related diseases. Helicobacter pylori and hepatitis A virus (HAV) are common fecal–oral infections. Our study aim...

    Authors: Christian S. Alvarez, M. Larissa Avilés-Santa, Neal D. Freedman, Krista M. Perreira, Olga Garcia-Bedoya, Robert C. Kaplan, Martha L. Daviglus, Barry I. Graubard, Gregory A. Talavera, Bharat Thyagarajan and M. Constanza Camargo

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:120

    Content type: Short Report

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  3. Increased levels of serum Immunoglobulin-E (IgE) and different genetic variants of cytokines are common biochemical manifestation in Allergy. The current study was aimed to study the association of IgE and dif...

    Authors: Taha Ashraf Qurashi, Aaliya Shah, Gulzar Ahmad Bhat, Mosin Saleem Khan, Roohi Rasool and Syed Mudassar

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:119

    Content type: Research

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  4. Allergic bronchopulmonary aspergillosis (ABPA) and chronic eosinophilic pneumonia (CEP) both display peripheral eosinophilia as well as pulmonary infiltration, together described as pulmonary eosinophilia, and...

    Authors: Mari Miki, Yuko Ohara, Kazuyuki Tsujino, Takahiro Kawasaki, Tomoki Kuge, Yuji Yamamoto, Takanori Matsuki, Keisuke Miki and Hiroshi Kida

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:118

    Content type: Research

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  5. Symptom control is a major concern in chronic urticaria. Histobulin™ is a histamine/immunoglobulin complex that has been approved for allergic rhinitis, bronchial asthma and chronic urticaria in some countries...

    Authors: Hyuk Soon Kim and Geunwoong Noh

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:116

    Content type: Case Report

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  6. Severe combined immunodeficiency (SCID) is a rare genetic condition characterized by significant T cell lymphopenia and impaired T cell function. Many jurisdictions use the quantitation of T cell receptor exci...

    Authors: Adil Adatia, Ling Ling, Pranesh Chakraborty, Lauren Brick and Rae Brager

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:115

    Content type: Letter to the Editor

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  7. Periplaneta americana and Blattella germanica cockroaches are widespread, and risk of sensitization increases in urban environments where these roaches thrive as household pests. There are no prior reports of Bla...

    Authors: Hannah Wangberg, Jun Mendoza, Robert Gomez, Christopher Coop, Andrew White and Katharine Woessner

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:114

    Content type: Case Report

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  8. Allergic rhinitis (AR) is the most common undiagnosed chronic condition in children. Moderate/severe AR symptoms significantly impair quality of life, and cause sleep disruption, absenteeism and decreased prod...

    Authors: Eli O. Meltzer, Nelson Augusto Rosario, Hugo Van Bever and Luiz Lucio

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:113

    Content type: Review

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  9. Treatment with immune checkpoint inhibitors has revolutionized cancer treatment over the past several years. Despite their clinical benefits, a wide range of immune-mediated toxicities can be observed includin...

    Authors: Romy G. Younan, Roy A. Raad, Bassem Y. Sawan and Rabih Said

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:112

    Content type: Case Report

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  10. Several primary studies evaluated the association between rhinitis and the incidence of depression and yielded inconsistent results. We conducted a meta-analysis of studies evaluating the association between r...

    Authors: Jing Wang, Dongqiong Xiao, Huayou Chen and Juan Hu

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:111

    Content type: Review

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  11. Intimacy-related allergic reactions, including anaphylaxis, are under-reported due to social stigma, lack of awareness, and misdiagnosis. The differential diagnosis for intimacy-related anaphylaxis is extensiv...

    Authors: Lundy R. McKibbin, Sidney Kin-Hung Siu, Hannah T. Roberts, Michael Shkrum and Samira Jeimy

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:110

    Content type: Case Report

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  12. Currently there is no systematic review and meta-analysis of the global incidence rates of anaphylactic and nonanaphylactic reactions to SARS-CoV-2 vaccines in the general adult population.

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Ali A. Rabaan, Raghavendra Tirupathi, Mohammed A. Alomari, Aqeel S. Alshakhes, Abeer M. Alshawi, Gasmelseed Y. Ahmed, Hassan M. Almusabeh, Tariq T. Alghareeb, Abdulaziz A. Alghuwainem, Zainab A. Alsulaiman, Mohammed A. Alabdulmuhsin, Emad A. AlBuwaidi, Amjad K. Bu Dukhi…

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:109

    Content type: Research

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  13. The Global Initiative for Asthma recommends the use of as-needed low-dose inhaled corticosteroid (ICS)-formoterol as a preferred controller therapy for patients with mild asthma. These recommendations were bas...

    Authors: Mohsen Sadatsafavi, J. Mark FitzGerald, Paul M. O’Byrne, Mena Soliman, Niroshan Sriskandarajah, Colin Vicente and Sarowar Muhammad Golam

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:108

    Content type: Research

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  14. Severe combined immunodeficiency (SCID) is a group of relatively rare primary immunodeficiency disorders (PIDs), characterized by disturbed development of T cells and B cells, caused by several genetic mutatio...

    Authors: Fatemeh Sadat Mahdavi, Mohammad Keramatipour, Sarina Ansari, Samin Sharafian, Arezou Karamzade and Marzieh Tavakol

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:107

    Content type: Case Report

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  15. The symptoms of patients with respiratory disease are influenced by local environmental factors. The incidence of allergic rhinitis in grassland areas was significantly higher than that in non-grassland areas....

    Authors: Xu Xu, Long Qin, Lei Ren, Chengshuo Wang, Yuan Zhang and Luo Zhang

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:106

    Content type: Research

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  16. Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and management options to reduce the burden of the COVID-19 disease are under investigation. IVIG therapy is used as an effective...

    Authors: Zahra Kolahchi, Hanye Sohrabi, Sara Ekrami Nasab, Hesan Jelodari Mamaghani, Maryam Keyfari Alamdari and Nima Rezaei

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:105

    Content type: Review

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  17. The determination of systemic inflammatory markers is one of the important directions to study the pathogenesis of asthma and improve the diagnosis of asthma. Current studies have found that the 14-3-3 protein...

    Authors: Decai Wang, Lizong Rao, Yalan Cui, Guoting Tang, Haiming Huang, Ting Yuan and Biwen Mo

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:104

    Content type: Research

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  18. C1 inhibitor (C1-INH) and complement 4 (C4) have historically been referred to as positive acute phase reactants, however this has never been evaluated in hereditary angioedema (HAE) patients. Low function of ...

    Authors: Peter Stepaniuk, Ana-Maria Bosonea, Persia Pourshahnazari, Adrienne Roos and Amin Kanani

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:103

    Content type: Case Report

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  19. Knowledge is limited about the relationship between clinical reactivity to foods through breastfeeding and long-term food allergy outcomes. We explored parent-perceived symptoms of food allergy via breastfeedi...

    Authors: Abigail Lang, Shrey Patel, Karen Rychlik, Deanna Caruso, Xiaobin Wang, Jacqueline A. Pongracic and Rajesh Kumar

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:102

    Content type: Research

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  20. Peanut and soybean allergies are listed as contraindication in the package leaflet of isotretinoin, a widely used treatment of acne vulgaris. Cross-reactivity between PR10-proteins in peanut, tree nuts, and so...

    Authors: Anna Bamidis and Silke C. Hofmann

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:101

    Content type: Case Report

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  21. Hereditary angioedema (HAE) is a rare genetic disorder characterized by unpredictable localized episodes of edema, which is frequently managed with long-term prophylactic medications. Until recently, long-term...

    Authors: Richard G. Gower and Mary Wilber

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:100

    Content type: Case Report

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  22. Jellyfish stings are known to induce allergic skin reactions; however, case reports of anaphylaxis after jellyfish ingestion have been increasing, especially in Asian countries. Some cases of anaphylaxis after...

    Authors: Mitsuru Tsuge, Masanori Ikeda, Osamu Mitani, Masato Yasui and Hirokazu Tsukahara

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:99

    Content type: Case Report

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  23. We present a case of CVID complicated by granulomatous interstitial lung disease (GLILD). This patient clinical course was further complicated by COVID-19 infection. This is only the 2nd known case report of C...

    Authors: Debendra Pattanaik, Shaunah Ritter and Joseph Fahhoum

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:98

    Content type: Case Report

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  24. Hen’s eggs are one of the most common causes of food allergy. Although hen’s eggs are known to cause more gastrointestinal symptoms than other foods, it is not known whether there is a difference in organ-spec...

    Authors: Kei Uneoka, Satoshi Horino, Ayafumi Ozaki, Haruka Aki, Masako Toda and Katsushi Miura

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:97

    Content type: Letter to the Editor

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  25. Atopic dermatitis is the most common chronic inflammatory skin disease and presents a major public health burden worldwide. Recent observational studies revealed the potential association between atopic dermat...

    Authors: Zhiyu Lu, Ni Zeng, Yuxin Cheng, Yihe Chen, Yueyue Li, Qian Lu, Qingyue Xia and Dan Luo

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:96

    Content type: Review

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  26. The prevalence of comorbidities and their relation to asthma control and treatment is a topic of increasing interest, however comprehensive studies are scarce. We aimed to determine the prevalence of the most ...

    Authors: Gábor Tomisa, Alpár Horváth, Balázs Sánta, András Keglevich and Lilla Tamási

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:95

    Content type: Research

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  27. It is well known that atopic dermatitis (AD) is associated with other allergic diseases. Recentely, links to diseases other than allergic disease have also been actively studied. Among them, the results of stu...

    Authors: Hye Jung Jung, Dong Heon Lee, Mi Youn Park and Jiyoung Ahn

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:94

    Content type: Research

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  28. There is currently a dramatic increase in the number of COVID-19 cases worldwide, and further drastic restrictions in our daily life will be necessary to contain this pandemic. The implications of restrictive ...

    Authors: Nicole Maison, Heidrun Herbrüggen, Bianca Schaub, Christina Schauberger, Svenja Foth, Ruth Grychtol, Mustafa Abdo, Henrik Watz, Wilfried Nikolaizik, Klaus F. Rabe, Matthias V. Kopp, Gesine Hansen, Erika von Mutius, Thomas Bahmer and Jimmy Omony

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:93

    Content type: Letter to the Editor

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  29. Allergen extracts used in subcutaneous immunotherapy can be standardized or non-standardized. Standardized extracts are available in specific biological potencies, presumably making their biological activity m...

    Authors: Benny Dua, Jane Park and Harold Kim

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:92

    Content type: Research

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  30. An allergy to kiwi is rare in Poland. Most (65–72%) of the patients who are allergic to kiwi report symptoms of an oral allergy syndrome (OAS); however, systemic manifestations (18–28%) have also been reported.

    Authors: Natalia Ukleja-Sokołowska, Robert Zacniewski, Kinga Lis, Magdalena Żbikowska-Gotz, Andrzej Kuźmiński and Zbigniew Bartuzi

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:91

    Content type: Case Report

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  31. Tocilizumab has been shown to be effective for treatment of juvenile idiopathic arthritis (JIA). To our knowledge, this is the first reported case of interstitial lung disease occurring shortly after tocilizum...

    Authors: Koichi Sugihara, Risa Wakiya, Hiromi Shimada, Mikiya Kato, Tomohiro Kameda, Shusaku Nakashima, Mai Mahmoud Fahmy Mansour, Yusuke Ushio, Norimitsu Kadowaki and Hiroaki Dobashi

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:90

    Content type: Case Report

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  32. Exercise-induced anaphylaxis (EIA) is a rare and potentially life-threatening disorder that can develop independently without food ingestion. Cold drinks can also trigger symptoms in some patients with cold-in...

    Authors: Chikako Motomura, Koji Ide, Terufumi Shimoda and Hiroshi Odajima

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:89

    Content type: Case Report

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  33. Toxic epidermal necrolysis (TEN)/Stevens–Johnson syndrome (SJS) is the spectrum of severe, acute, mucocutaneous, T-cell mediated delayed type IV hypersensitivity reaction and universally related to different d...

    Authors: Biniyam A. Ayele, Kemal Ali and Eliyas Mulatu

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:88

    Content type: Case Report

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  34. A formulation of black cumin (Nigella sativa L.), licorice (Glycyrrhiza glabra L.), anise (Pimpinella anisum L.) and tea (Camellia sinensis (L.) Kuntze) (denoted BLAB tea) is traditionally used to relief allergy ...

    Authors: Chengsong Liao, Yangyang Han, Zhijing Chen and Huricha Baigude

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:87

    Content type: Research

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  35. Increased intestinal permeability, either due to the exposure to antigens in asthmatic patients or due to a barrier defect, plays a critical role in susceptibility to environmental allergens. House dust mite a...

    Authors: Shereen A. Baioumy, Aya Elgendy, Shereen M. Ibrahim, Sara I. Taha and Shaimaa H. Fouad

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:86

    Content type: Research

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  36. Leveraging the data management resources of the Canadian Primary Care Sentinel Surveillance Network (CPCSSN) is a viable approach for describing the prevalence of allergic disease documented in primary care se...

    Authors: Alexander G. Singer, Leanne Kosowan, Nerissa Nankissoor, Ryan Phung, Jennifer L. P. Protudjer and Elissa M. Abrams

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:85

    Content type: Short Report

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  37. Physical effort is capable of triggering airway obstruction in asthmatics, the so-called exercise-induced bronchoconstriction in asthma (EIBa). This study was performed in subjects with mild persistent asthma,...

    Authors: Maroon Salameh, Laura Pini, Federico Quadri, Fabio Spreafico, Damiano Bottone and Claudio Tantucci

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:84

    Content type: Research

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  38. Food ladders are clinical tools already widely used in Europe for food reintroduction in milk- and egg-allergic children. Previously developed milk and egg ladders have limited applicability to Canadian childr...

    Authors: Alanna Chomyn, Edmond S. Chan, Joanne Yeung, Timothy K. Vander Leek, Brock A. Williams, Lianne Soller, Elissa M. Abrams, Raymond Mak and Tiffany Wong

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:83

    Content type: Letter to the Editor

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  39. The expression profiles of the intestinal mucosa have not been comprehensively investigated in asthma. We aimed to explore this in the Correlated Expression and Disease Association Research (CEDAR) patient coh...

    Authors: Jan K. Nowak, Marzena Dworacka, Nazgul Gubaj, Arystan Dossimov, Zhumabek Dossimov and Jarosław Walkowiak

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:82

    Content type: Research

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  40. Drug reaction with eosinophilia and systemic symptoms (DRESS) is a potentially life-threatening hypersensitivity reaction to medication. While a relatively rare phenomenon, early identification and discontinua...

    Authors: Arman Zereshkian and Susan Waserman

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:81

    Content type: Case Report

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  41. Allergic reaction to liposomal amphotericin B is rare. We report a case of cardiac arrest in a 64-year-old woman following liposomal amphotericin B infusion, requiring resuscitation. We also present the result...

    Authors: George P. Drewett, Ana Copaescu, Joseph DeLuca, Natasha E. Holmes and Jason A. Trubiano

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:80

    Content type: Case Report

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  42. Insulin hypersensitivity is rare, but challenging for individuals with diabetes. The prevalence of insulin allergy has decreased since the introduction of human recombinant insulin preparations. Hypersensitivi...

    Authors: Babak Aberumand and Samira Jeimy

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:79

    Content type: Case Report

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  43. Hereditary angioedema (HAE) is a rare autosomal dominant disease resulting in recurring episodes of swelling, leading to considerable patient morbidity and mortality. Lanadelumab is a plasma kallikrein inhibit...

    Authors: Aled Iaboni, Amin Kanani, Gina Lacuesta, Christine Song, Manstein Kan and Stephen D. Betschel

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:78

    Content type: Letter to the Editor

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  44. Body mass index (BMI) is associated with asthma but associations of BMI temporal patterns with asthma incidence are unclear. Previous studies suggest that DNA methylation (DNAm) is associated with asthma statu...

    Authors: Rutu Rathod, Hongmei Zhang, Wilfried Karmaus, Susan Ewart, Latha Kadalayil, Caroline Relton, Susan Ring, S. Hasan Arshad and John W. Holloway

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:77

    Content type: Research

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  45. Shrimp allergy is a growing problem among the European population. TSLP, IL-25 and IL-33 are involved in the pathophysiology of allergic diseases, including asthma and atopic dermatitis, as they activate the T...

    Authors: Natalia Ukleja-Sokołowska, Magdalena Żbikowska-Gotz, Kinga Lis, Rafał Adamczak and Zbigniew Bartuzi

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:76

    Content type: Research

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  46. Currently, several biologics are used for the treatment of cutaneous pathologies such as atopic dermatitis (AD), psoriasis or skin cancers. The main administration routes are subcutaneous and intravenous injec...

    Authors: Audrey Baylet, Raoul Vyumvuhore, Marine Laclaverie, Laëtitia Marchand, Carine Mainzer, Sylvie Bordes, Brigitte Closs-Gonthier and Laurent Delpy

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:73

    Content type: Short Report

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  47. We conducted a nationwide Canadian telephone survey on food allergy prevalence between February 2016 and January 2017, targeting vulnerable populations (New, Indigenous, and lower-income Canadians).

    Authors: Ann E. Clarke, Susan J. Elliott, Yvan St. Pierre, Lianne Soller, Sebastien La Vieille and Moshe Ben-Shoshan

    Citation: Allergy, Asthma & Clinical Immunology 2021 17:72

    Content type: Letter to the Editor

    Published on:

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