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  1. Over the last decade, our group has demonstrated that murine preconception immunization with allergens has a protective effect on allergy development in offspring. The murine model used in the present study al...

    Authors: Aline Aparecida de Lima Lira, Marília Garcia de Oliveira, Luana Mendonça de Oliveira, Alberto José da Silva Duarte, Maria Notomi Sato and Jefferson Russo Victor
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:47
    Content type: Short report Published on:

  2. Allergic conditions in children are a prevalent health concern in Canada. The burden of disease and the societal costs of proper diagnosis and management are considerable, making the primary prevention of alle...

    Authors: Edmond S Chan, Carl Cummings, Adelle Atkinson, Zave Chad, Marie-Josée Francoeur, Linda Kirste, Douglas Mack, Marie-Noël Primeau, Timothy K Vander Leek and Wade TA Watson
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:45
    Content type: Position article and guidelines Published on:

  4. Regulatory T cells (Tregs) play a key role in immune homeostasis in vivo. Tregs have a critical role in preventing the development of autoimmune diseases and defects in Treg function are implicated in various ...

    Authors: Mladen Jergović, Krešo Bendelja, Anđelko Vidović, Ana Savić, Valerija Vojvoda, Neda Aberle, Sabina Rabatić, Tanja Jovanovic and Ante Sabioncello
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:43
    Content type: Research Published on:

  5. Due to its high allergenic potential Ambrosia artemisiifolia has become a health threat in many European countries during the last few decades. Hence, several cities and communities initiated ragweed eradication ...

    Authors: Oliver Brandt, Torsten Zuberbier and Karl-Christian Bergmann
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:42
    Content type: Short report Published on:

  6. There has been a significant growth in the prevalence of allergy, mainly associated to IgE-mediated disorders such as asthma and rhinitis. The identification of atopy in asthmatic patients through the measurem...

    Authors: Fardis Teifoori, Masoomeh Shams-Ghahfarokhi, Idoia Postigo, Mehdi Razzaghi-Abyaneh, Ali Eslamifar, Antonio Gutiérrez, Ester Suñén and Jorge Martínez
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:41
    Content type: Research Published on:

  7. The Epipen® Jr and Allerject® 0.15 mg are currently the most commonly prescribed epinephrine auto-injectors (EAIs) for the management of anaphylaxis in pediatric patients in North America and Canada. To ensure...

    Authors: Laura Kim, Immaculate FP Nevis, Gina Tsai, Arunmozhi Dominic, Ryan Potts, Jack Chiu and Harold L Kim
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:40
    Content type: Research Published on:

  8. Epinephrine auto-injectors are the standard first aid treatment for anaphylaxis. Intramuscular delivery into the anterolateral aspect of the thigh is recommended for optimal onset of action of epinephrine. The...

    Authors: Gina Tsai, Laura Kim, Immaculate FP Nevis, Arunmozhi Dominic, Ryan Potts, Jack Chiu and Harold L Kim
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:39
    Content type: Research Published on:

  9. Examining deaths caused by anaphylaxis may help identify factors that may decrease the risk of these unfortunate events. However, information on fatal anaphylaxis is limited. The objectives of our study were t...

    Authors: Ya Sophia Xu, Monika Kastner, Laurie Harada, Anna Xu, Jane Salter and Susan Waserman
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:38
    Content type: Research Published on:

  11. Oral immunotherapy (OIT) has shown promise in inducing desensitization for food allergy. However, there are safety concerns regarding the frequency and severity of adverse events during food OIT.

    Authors: Amanda Jagdis, Noam Berlin, Carly Barron, Mohana Giruparajah, Nathan Leader, Sean Maclachlan and Gordon L Sussman
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:36
    Content type: Research Published on:

  12. In recent decades there has been an increase in the prevalence of allergic disease. Manifestations of these diseases have allegedly been observed in people living with Human Immunodeficiency Virus (HIV), howev...

    Authors: Leandro S Linhar, Jefferson Traebert, Dayani Galato, Rosemeri M da Silva, Fabiana Schuelter-Trevisol, Natália S Rovaris and Jane da Silva
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:35
    Content type: Research Published on:

  13. Thiazolidinediones are oral diabetes medications that selectively activate peroxisome proliferator-activated receptor gamma and have potent anti-inflammatory properties. While a few studies have found improvem...

    Authors: Seppo T Rinne, Laura C Feemster, Bridget F Collins, David H Au, Mark Perkins, Christopher L Bryson, Thomas G O’Riordan and Chuan-Fen Liu
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:34
    Content type: Research Published on:

  14. Oral antihistamines that target the histamine receptor–1, such as fexofenadine, offer suboptimal relief of allergic rhinitis-associated nasal congestion. Combinations with oral sympathomimetics, such as pseudo...

    Authors: Michelle L North, Terry J Walker, Lisa M Steacy, Barnaby G Hobsbawn, Richard J Allan, Frances Hackman, Xiaoqun Sun, Andrew G Day and Anne K Ellis
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:33
    Content type: Research Published on:

  15. The imbalance between Th17 and Treg cells has been studied in various diseases including allergic asthma but their roles have not been fully understood in the development of the late phase asthmatic response.

    Authors: Amrit Singh, Masatsugu Yamamoto, Jian Ruan, Jung Young Choi, Gail M Gauvreau, Sven Olek, Ulrich Hoffmueller, Christopher Carlsten, J Mark FitzGerald, Louis-Philippe Boulet, Paul M O'Byrne and Scott J Tebbutt
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:32
    Content type: Research Published on:

  16. There is conflicting evidence about the association between low vitamin D levels in children and development of asthma in later life. The objective of this study was to systematically review the evidence for a...

    Authors: Mhd Hashem Rajabbik, Tamara Lotfi, Lina Alkhaled, Munes Fares, Ghada El-Hajj Fuleihan, Salman Mroueh and Elie A Akl
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:31
    Content type: Research Published on:

  17. A previous study has shown that the aggravation of Asian sand dust (ASD) on ovalbumin (OVA)-induced lung eosinphilia was more severe in lipopolysaccharide (LPS)-rich ASD than in SiO2-rich ASD. Therefore, the effe...

    Authors: Yahao Ren, Takamichi Ichinose, Miao He, Yuan Song, Yasuhiro Yoshida, Seiichi Yoshida, Masataka Nishikawa, Hirohisa Takano, Guifan Sun and Takayuki Shibamoto
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:30
    Content type: Research Published on:

  18. Second generation H1 antihistamines (H1A) are currently recommended as first choice medications for allergic rhinitis and rhinoconjunctivitis. However, little is known about what influences the choice of presc...

    Authors: Pascal Demoly, Anca Mirela Chiriac, Benoît Berge and Michel Rostin
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:29
    Content type: Research Published on:

  19. Tuberculous pleurisy is a kind of tuberculosis, it is well known that Th1 lymphocytes play a key role in the treatment of tuberculosis infection. However, latest studies show that Th17 lymphocyte may also play...

    Authors: Guo-qiang Wang, Cai-ling Yang, Dong-fang Yue, Li-hong Pei, Hua Zhong and Ju-xia Niu
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:28
    Content type: Research Published on:

  20. Epigenetics of asthma and allergic disease is a field that has expanded greatly in the last decade. Previously thought only in terms of cell differentiation, it is now evident the epigenetics regulate many pro...

    Authors: Philippe Bégin and Kari C Nadeau
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:27
    Content type: Review Published on:

  22. Food allergy (FA) negatively affects quality of life in caregivers of food-allergic children, imposing a psychosocial and economic burden. Oral immunotherapy (OIT) is a promising investigational therapy for FA...

    Authors: Iris M Otani, Philippe Bégin, Clare Kearney, Tina LR Dominguez, Anjuli Mehrotra, Liane R Bacal, Shruti Wilson and Kari Nadeau
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:25
    Content type: Research Published on:

  23. A significant proportion of patients with chronic urticaria respond inadequately to first line treatment with antihistamines. Leukotreine receptor antagonists (LTRA) are also used for chronic urticaria, althou...

    Authors: Nipun Lakshitha de Silva, Hasitha Damayanthi, Anoja Chamarie Rajapakse, Chaturaka Rodrigo and Senaka Rajapakse
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:24
    Content type: Review Published on:

  24. Switching primary/secondary immunodeficiency (PID/SID) patients from intravenous immunoglobulin (IVIg) to home-based subcutaneous immunoglobulin (SCIg) therapy reduces nurse time. A nurse shortage in Canada pr...

    Authors: William C Gerth, Stephen D Betschel and Arthur S Zbrozek
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:23
    Content type: Short report Published on:

  25. Allergen-specific subcutaneous immunotherapy is an effective treatment for certain allergic disorders. Ideally, it should be administered into the subcutaneous space in the mid-posterolateral upper arm. Inject...

    Authors: Laura Kim, Immaculate Nevis, Ryan Potts, Clark Eeuwes, Arunmozhi Dominic and Harold L Kim
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:22
    Content type: Research Published on:

  26. Asthma is the most common chronic disease of childhood and a leading cause of childhood morbidity. The aim of the current study was to assess the effectiveness of montelukast administered as monotherapy or in ...

    Authors: Denis Bérubé, Michel Djandji, John S Sampalis and Allan Becker
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:21
    Content type: Research Published on:

  27. Platelet-activating factor (PAF) is a highly potent phospholipid mediator responsible for the life-threatening manifestations of anaphylaxis. PAF acetylhydrolase (PAF-AH) inactivates PAF and protects against s...

    Authors: Boris Perelman, Areej Adil and Peter Vadas
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:20
    Content type: Short report Published on:

  28. It is hypothesized that because of higher mast cell numbers and mediator release, mastocytosis predisposes patients for systemic immediate-type hypersensitivity reactions to certain drugs including non-steroid...

    Authors: Cornelia S Seitz, Knut Brockow, Johannes Hain and Axel Trautmann
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:19
    Content type: Research Published on:

  29. Inhaled medications are the cornerstone of asthma therapy. Metered dose inhaler technique is a widely used technique to administer medications like corticosteroids. Meanwhile, the health professionals and pati...

    Authors: Hussen D Ali, Gubena S Worku, Asfaw A Alemayehu and W/aregay H Gebrehiwot
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:18
    Content type: Research Published on:

  30. Hereditary Angioedema (HAE) is a rare autosomal dominant condition characterized by episodic angioedema, which may be triggered by invasive procedures and surgery. C1 inhibitor (C1 INH) was approved in the Uni...

    Authors: Geneviève Gavigan, William H Yang, Stephanie Santucci, Rachel Harrison and Jacob Karsh
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:17
    Content type: Research Published on:

  32. Chronic rhinosinusitis (CRS) is a societal burden and cause of morbidity in Canada; however, the prevalence of allergic sensitization in Canadian CRS patients has remained poorly characterized.

    Authors: Brett J Green, Donald H Beezhold, Zane Gallinger, Carly S Barron, Rochelle Melvin, Toni A Bledsoe, Michael L Kashon and Gordon L Sussman
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:15
    Content type: Research Published on:

  33. Fairly recent data highlight the role of programmed cell death and autoimmunity, as potentially important factors in the pathogenesis of chronic obstructive airway diseases. The purpose of our research was to ...

    Authors: Cyrille Alode Vodounon, Christophe Boni Chabi, Ylia Valerevna Skibo, Vincent Ezin, Nicolas Aikou, Simeon Oloni Kotchoni, Simon Ayeleroun Akpona, Lamine Baba-Moussa and Zinaida Ivanovna Abramova
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:14
    Content type: Research Published on:

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