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Research
Antagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein coupled receptor for prostaglandin D2, could be beneficial for treating allergic disorders. We present f...
Allergy, Asthma & Clinical Immunology 2017 13:18
Published on: 4 April 2017
Research
Food allergen labeling is an important tool to reduce risk of exposure and prevent anaphylaxis for individuals with food allergies. Health Canada released a Canadian food allergen labeling regulation (2008) an...
Allergy, Asthma & Clinical Immunology 2017 13:19
Published on: 4 April 2017
Research
It is well-known that lymphocytes play an important role in systemic lupus erythematosus (SLE). T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory domains (TIGIT) is one of immunosuppre...
Allergy, Asthma & Clinical Immunology 2017 13:15
Published on: 28 February 2017
Research
Asthma is an increasingly common chronic disease among children, and data point toward a complex mechanism involving genetic, environmental and epigenetic factors. Epigenetic modifications such as DNA hypo- or...
Allergy, Asthma & Clinical Immunology 2017 13:12
Published on: 27 February 2017
Review
The use of gene therapy (GT) for the treatment of primary immune deficiencies (PID) including severe combined immune deficiency (SCID) has progressed significantly in the recent years. In particular, long-term...
Allergy, Asthma & Clinical Immunology 2017 13:14
Published on: 27 February 2017
Case Report
Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injectio...
Allergy, Asthma & Clinical Immunology 2017 13:13
Published on: 23 February 2017
Letter to the editor
As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House d...
Allergy, Asthma & Clinical Immunology 2017 13:11
Published on: 21 February 2017
Research
Peanut sensitization does not necessarily indicate clinical peanut allergy, and uncertainty as to whether or not there is true peanut allergy can lead to increased anxiety and decreased quality of life for pat...
Allergy, Asthma & Clinical Immunology 2017 13:10
Published on: 8 February 2017
Research
We aimed to determine the effect of sampling time during the day on serum periostin levels in adult participants with and without asthma.
Allergy, Asthma & Clinical Immunology 2017 13:8
Published on: 8 February 2017
Research
The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More impo...
Allergy, Asthma & Clinical Immunology 2017 13:9
Published on: 8 February 2017
Letter to the editor
The Addendum Guidelines for the Prevention of Peanut Allergy in the United States—Report of the NIAID-Sponsored Expert Panel were developed to build on previous food allergy guidelines after several key studies d...
Allergy, Asthma & Clinical Immunology 2017 13:7
Published on: 8 February 2017
Case report
Patients with atopic dermatitis have a predisposition to Staphylococcus aureus and a Herpes simplex virus infection. The treatment of atopic diseases with steroid and immunosuppressive agents induces opportunisti...
Allergy, Asthma & Clinical Immunology 2017 13:6
Published on: 25 January 2017
Research
Shrimp and house dust mite (HDM) allergies are common in Canadians. Often, both of these allergies occur in the same patient. This may be due to homology of tropomyosin or other potentially shared proteins. Th...
Allergy, Asthma & Clinical Immunology 2017 13:5
Published on: 19 January 2017
Short report
Hereditary angioedema (HAE) is a rare but serious condition characterized by recurrent spontaneous attacks of angioedema affecting superficial tissues of upper respiratory and gastrointestinal tracts. The pote...
Allergy, Asthma & Clinical Immunology 2017 13:4
Published on: 19 January 2017
Review
Asthma is a chronic inflammatory immune disorder of the airways affecting one in ten children in westernized countries. The geographical disparity combined with a generational rise in prevalence, emphasizes th...
Allergy, Asthma & Clinical Immunology 2017 13:3
Published on: 6 January 2017
Position article and guidelines
Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institut...
Allergy, Asthma & Clinical Immunology 2017 13:1
Published on: 6 January 2017
Case report
Anti-interleukin (IL)-5 monoclonal antibodies as an eosinophil-depleting strategy is well established, with Mepolizumab being the first biologic approved as an adjunct treatment for severe eosinophilic asthma.
Allergy, Asthma & Clinical Immunology 2017 13:2
Published on: 6 January 2017
Case report
Anaphylactic reactions involving IgE mediated hypersensitivity have been frequently reported for a number of uncommon foods. However, cases of anaphylaxis to over the counter vitamins and oral supplements have...
Allergy, Asthma & Clinical Immunology 2016 12:66
Published on: 13 December 2016
Case report
Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food.
Allergy, Asthma & Clinical Immunology 2016 12:67
Published on: 13 December 2016
Meeting abstracts
Allergy, Asthma & Clinical Immunology 2016 12(Suppl 2):63
Published on: 8 December 2016
This article is part of a Supplement: Volume 12 Supplement 2
Research
New Zealand is a developed geographically isolated country in the South Pacific with a population of 4.4 million. Genetic diagnosis is the standard of care for most patients with primary immunodeficiency disor...
Allergy, Asthma & Clinical Immunology 2016 12:65
Published on: 7 December 2016
Case report
Aspergillus is a ubiquitous fungus responsible for allergic as well as saprophytic and invasive manifestations depending on host’s immune status. The following case report demonstrates...
Allergy, Asthma & Clinical Immunology 2016 12:64
Published on: 3 December 2016
Research
Primary immunodeficiency (PID) is a heterogeneous group of inheritable genetic disorders with increased susceptibility to infections, autoimmunity, uncontrolled inflammation and malignancy. Timely precise diag...
Allergy, Asthma & Clinical Immunology 2016 12:62
Published on: 2 December 2016
Research
Component resolved allergen diagnosis allows for a precise evaluation of the sensitization profiles of patients sensitized to felines and canines. An accurate interpretation of these results allows better insi...
Allergy, Asthma & Clinical Immunology 2016 12:61
Published on: 30 November 2016
Research
Research suggests that 90% of patients labeled beta-lactam allergic are able to tolerate penicillins following further assessment. This study aims to define and describe the frequency of true beta-lactam aller...
Allergy, Asthma & Clinical Immunology 2016 12:59
Published on: 29 November 2016
The official journal of CSACI
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