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  1. Most asthma diagnoses and patient care take place in primary care settings. Electronic medical records (EMRs) offer an opportunity to utilize technology to improve asthma diagnosis and care. The purpose of thi...

    Authors: Max Moloney, Alison Morra, Rachael Morkem, John Queenan, Samir Gupta, Teresa To, Geneviève Digby, David Barber and M. Diane Lougheed
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:95
  2. Food ladders are tools designed to facilitate home-based dietary advancement in children with food allergies through stepwise exposures to increasingly allergenic forms of milk and egg. Several studies have no...

    Authors: Alanna Chomyn, Edmond S. Chan, Joanne Yeung, Scott Cameron, Gilbert T. Chua, Timothy K. Vander Leek, Brock A Williams, Lianne Soller, Elissa M. Abrams, Raymond Mak and Tiffany Wong
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:94
  3. Osimertinib has emerged as an important tool in the treatment of non-small cell lung cancers (NSCLC) with certain activating mutations of epidermal growth factor receptor (EGFR). However, Osimertinib may cause...

    Authors: Michael Lopez, Garo Hagopian, Linda Doan, Benjamin J. Lee, Nathan W. Rojek, Janellen Smith, Sai-Hong Ignatius Ou, Yesim Yilmaz Demirdag and Misako Nagasaka
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:93
  4. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare but severe and sometimes fatal adverse drug reaction that is known to occur with a number of antiepileptic drugs. It often follo...

    Authors: Khanh Duy Doan, Adeyinka Akinsanya, Matthew Kuhar and Hector Mesa
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:92
  5. There is an urgent need to understand the interplay between SARS-CoV-2 and HIV to inform risk-mitigation approaches for HIV-infected individuals.

    Authors: Shima Shahbaz, Wendy Sligl, Mohammed Osman and Shokrollah Elahi
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:91
  6. Dupilumab, omalizumab, and mepolizumab are the three biologics currently approved for use in CRSwNP in Canada. Despite evidence of efficacy, their cost-effectiveness, which is a key factor influencing prescrib...

    Authors: Michael Yong, Keshinisuthan Kirubalingam, Martin Y. Desrosiers, Shaun J. Kilty and Andrew Thamboo
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:90
  7. Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects children and adults. Poor treatment adherence in AD requires interventions to promote self-management; patient education in chronic di...

    Authors: Bethany Wilken, M. Zaman and Y. Asai
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:89
  8. Penicillin allergy is the most commonly reported drug allergy in the US. Despite evidence demonstrating that up to 90% of labels are incorrect, scalable interventions are not well established. As part of a lar...

    Authors: Esra Alagoz, Megan Saucke, Prakash Balasubramanian, Paul Lata, Tyler Liebenstein and Sujani Kakumanu
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:88
  9. Current management of food protein-induced enterocolitis syndrome (FPIES) involves strict avoidance of the offending food for 12–18 months, followed by oral food challenge (OFC) under physician supervision. OF...

    Authors: Linlei Ye, Tiffany Wong, Elana Lavine, Victoria E. Cook and Stephanie C. Erdle
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:87
  10. Activated phosphoinositide3-kinase (PI3K) δ syndrome 1 (APDS1) is a novel inborn errors of immunity (IEIs) caused by heterozygous gain of function mutations in PI3Kδ catalytic p110δ (PIK3CD). APDS1 has a spect...

    Authors: Lu Jiang, Xiaohan Hu, Qiang Lin, Ruyue Chen, Yunyan Shen, Yun Zhu, Qinying Xu and Xiaozhong Li
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:86
  11. Canada has high immunoglobulin (IG) product utilization, raising concerns about appropriate utilization, cost and risk of shortages. Currently, there is no national set of standardized IG guidelines, and consi...

    Authors: Megan Harmon, Kiarash Riazi, Jeannie Callum, Donald M. Arnold, Rebecca Barty, Davinder Sidhu, Nancy M. Heddle, Laurie MacLeod and Na Li
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:85
  12. Idiopathic Anaphylaxis (IA) is the most common anaphylactic syndrome in adults. Mental health problems associated with IA are not well recognised. We aimed to assess if patients diagnosed with IA were more lik...

    Authors: Logan S Gardner, Zihao Tan, David Brown, David Gillis, James G. Scott and Roger Prentice
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:84
  13. To investigate the role of combined impulse oscillometry (IOS) and fractional exhaled nitric oxide (FeNO) in the diagnosis of cough variant asthma (CVA) in preschool children.

    Authors: Ying Hu, Shouyan Zheng, Zhiqiang Chen, Dan Yu, Tianxia Lai, Yao Chen and Wei Liao
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:83
  14. Anaphylaxis is an acute, potentially life-threatening allergic reaction that typically occurs after exposure to a trigger, while idiopathic anaphylaxis (IA) occurs in the absence of a trigger. Acute management...

    Authors: Elizabeth Pepper and Luke Pittman
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:82
  15. The prevalence of eosinophilic asthma in Lebanon, one of the most severe phenotypes among severe asthma, is not known. This study aimed at determining the prevalence of the eosinophilic phenotype defined as an...

    Authors: Wajdi Abi Saleh, Zuhair Alameh, Zeina Aoun Bacha, Joudy Bahous, Pierre Bou Khalil, Zahia Chahine, Hassan Chami, Georges Dabar, Hassan Dheiny, Alfred Dib, Dany farhat, Carla Irani, Georges Juvelekian, Nadim Kanj, Bassam Mansour, Moussa Riachi…
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:80
  16. Interleukin (IL)-36 family cytokines have received increasing attention, especially in the fields of inflammation and immunity research. However, whether IL-36 family cytokine levels are correlated with the re...

    Authors: Jia Gu, Gang Qin, Liang Jiang, Wei Xu, Yuanyuan Wang, Jiangxue Liao, Hongzhu Pan and Zhuoping Liang
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:79
  17. Autophagy protein 5 (ATG5) regulates airway epithelial cell autophagy, immune response, and inflammation, which is involved in asthma progression. This study aimed to evaluate ATG5 levels and its clinical role...

    Authors: Changjiang Ke and Sheng Xie
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:77
  18. Respiratory conditions, such as asthma, are infrequently associated with auto-inflammatory diseases. We describe five patients with uncontrolled respiratory symptoms that were seen at St. Joesph’s Healthcare i...

    Authors: Bashayr M. Alotaibi, Raquel Lopez Rodriguez, Carmen Venegas Garrido, Lucia Gonzalez Bravo, Nader Khalidi and Parameswaran Nair
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:76
  19. Immunoglobulin A deficiency (IgAD) is a common disease with an unknown genetic defect, characterized by the decreased or absent IgA with other isotypes normal, normal subclasses, and specific antibodies. Patie...

    Authors: Ahmad Vosughimotlagh, Seyed Erfan Rasouli, Hosein Rafiemanesh, Molood Safarirad, Niusha Sharifinejad, Atossa Madanipour, Maria Marluce Dos Santos Vilela, Edyta Heropolitańska-Pliszka and Gholamreza Azizi
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:75
  20. The market share of foods carrying labels suggesting absence of animal ingredients has significantly increased in recent years. The purpose of this study was to document the purchasing behaviour of egg- or mil...

    Authors: Silvia Dominguez, Jérémie Théolier, Kamila Lizée, Beatrice Povolo, Jennifer Gerdts and Samuel B. Godefroy
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:74
  21. Asthma is a chronic airway inflammatory disease that affects millions of Canadians and often contributes to higher levels of anxiety among patients. Since the coronavirus disease 2019 (COVID-19) pandemic was a...

    Authors: Sophia Linton, Kayley Xu, Lubnaa Hossenbaccus, Hannah Botting, Sarah Garvey, Adam Sunavsky, Lisa M. Steacy, Dean A. Tripp and Anne K. Ellis
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:73
  22. The rate of cytomegalovirus (CMV) retinitis is increasing, likely secondary to aggressive immunosuppressive regimens for a variety of diseases. Transplant and rheumatological literature show growing evidence s...

    Authors: Prem N. Patel, Ahmed M. Alkaliby, Mitul C. Mehta and Angeline L. Wang
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:72
  23. Real world data on the response to the SARS-CoV-2 vaccine in patients with immunomediated diseases (IMIDs) treated with immunesuppressants is of great interest because vaccine response may be impaired. The mai...

    Authors: Chamaida Plasencia-Rodríguez, Ana Martínez-Feito, Marta Hernández, Lucia Del Pino-Molina, Marta Novella-Navarro, Yolanda Serrano, Miguel González-Muñoz, Diana Peiteado, Gema Bonilla, Irene Monjo, Laura Nuño, Carolina Tornero, Eduardo López-Granados, Alejandro Balsa and Pilar Nozal
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:71
  24. Allergy to chicken egg protein is a common form of food allergy. The most common clinical presentation includes gastrointestinal, skin, and respiratory symptoms. Differential diagnosis, including provocative t...

    Authors: E. Krzych-Fałta, O. Wojas, P. Samel-Kowalik, B. Samoliński, A. Sybilski and S. Białek
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:70
  25. Inborn errors of immunity (IEIs) are considered significant challenges for children with IEIs, their families, and their medical providers. Infections are the most common complication of IEIs and children can ...

    Authors: Saad Alhumaid, Koblan M. Al Mutared, Zainab Al Alawi, Zainah Sabr, Ola Alkhars, Muneera Alabdulqader, Nourah Al Dossary, Fatemah M. ALShakhs, Rabab Abbas Majzoub, Yousef Hassan Alalawi, Khalid Al Noaim, Abdulrahman A. Alnaim, Mohammed A. Al Ghamdi, Abdulaziz A. Alahmari, Sawsan Sami Albattat, Yasin S. Almubarak…
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:69
  26. Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency caused by mutations in the WAS gene that leads to increased susceptibility to infections, thrombocytopenia, eczema, malignancies, and autoimm...

    Authors: Vivien X. Xie, Wilson File, Christina Wiedl, Brant R. Ward, Blachy Dávila Saldaña, Michael D. Keller and Alexandra B. Kornbluh
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:68
  27. Aspirin-exacerbated respiratory disease (AERD) and IgG4-related disease (IgG4RD) share a common pathway of Th2-mediated immune mechanism; there have been several cases of IgG4RD developed in patients with asth...

    Authors: Hyun-Seob Jeon, Jae-Hyuk Jang, Youngsoo Lee and Hae-Sim Park
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:67
  28. Treatment of cystic fibrosis (CF) has been revolutionized by the use of cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators such as elexacaftor/tezacaftor/ivacaftor (ETI) triple thera...

    Authors: A. M. Mehta, I. Lee, G. Li, M. K. Jones, L. Hanson, K. Lonabaugh, R. List, L. Borish and D. P. Albon
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:66
  29. Approximately 6–7% of Canadian children have food allergy. These families face substantial burdens due to the additional costs incurred purchasing allergy-friendly products necessary for management compared to...

    Authors: Manvir Bhamra, Zoe Harbottle, Michael A Golding, Moshe Ben-Shoshan, Leslie E Roos, Elissa M Abrams, Sara J Penner, Jo-Anne St-Vincent and Jennifer LP Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:65
  30. Recurring therapy resistant hives, accompanied by IgM-gammopathy, fever and joint pain can indicate Schnitzler syndrome, a rare autoimmune disorder. There is currently no approved treatment, but complete remis...

    Authors: Viktoria Puxkandl, Antonia Currie, Wolfram Hoetzenecker and Sabine Altrichter
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:64
  31. Food allergy affects 7-8% of children worldwide. Teachers supervise children in school, where most children spend their day. Yet, teachers have variable food allergy-related knowledge.

    Authors: Mae Jhelene L. Santos, Kaitlyn Merrill, Natalie Riediger, Elissa M. Abrams, Nathalie Piquemal, Elinor Simons and Jennifer L.P. Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:62
  32. Secukinumab has been approved by the U.S. FDA and the European Medicines Agency for the treatment of moderate-to-severe plaque psoriasis and psoriatic arthritis with the documented adverse effects. Here we rep...

    Authors: Qingqing Yang, Jiajie Lyu, Yu Gui, Shuling Yu, Jiajie Chen, Haoxue Zhang and Shengxiu Liu
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:59
  33. “Epidemiology of comorbidities and their association with asthma control” (Tomisa, G., Horváth, A., Sánta, B. et al. Epidemiology of comorbidities and their association with asthma control. Allergy Asthma Clin Im...

    Authors: Diego M. Conti, Peter W. Hellings, Zuzana Diamant, Leif Bjermer, Milos Jesenak, Vibeke Backer, Wytske Fokkens, Susanne Lau, Elizabeth Van Staeyen and Glenis K. Scadding
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:56
  34. Helminth/tuberculosis (TB)-coinfection can reduce cell-mediated immunity against Mycobacterium tuberculosis (Mtb) and increase disease severity, although the effects are highly helminth species dependent. Mtb hav...

    Authors: Giggil Pushpamithran, Camilla Skoglund, Fanny Olsson, Melissa Méndez-Aranda, Thomas Schön, Mårten Segelmark, Olle Stendahl, Robert H. Gilman and Robert Blomgran
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:55
  35. Authors: Paul K. Keith, Juthaporn Cowan, Amin Kanani, Harold Kim, Gina Lacuesta, Jason K. Lee, Jie Chen, Michelle Park and André Gladiator
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:54

    The original article was published in Allergy, Asthma & Clinical Immunology 2022 18:70

  36. Allergic disease is on the rise. Waitlists for specialists are long, and many referred patients have already received prior allergic assessment, either by a certified Allergist, Primary Care Provider, or other...

    Authors: Adam P. Sage, Elliot James, Megan Burke, Edmond S. Chan and Tiffany Wong
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:52
  37. Severe Congenital Neutropenia type 4 (SCN4), is a rare autosomal recessive condition, due to mutations in the G6PC3 gene. The phenotype comprises neutropenia of variable severity and accompanying anomalies.

    Authors: Negar Moradian, Samaneh Zoghi, Elham Rayzan, Simin Seyedpour, Raul Jimenez Heredia, Kaan Boztug and Nima Rezaei
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:51
  38. The effects of nicotine and cigarette smoke in many diseases, notably COVID-19 infection, are being debated more frequently. The current basic data for COVID-19 is increasing and indicating the higher risk of ...

    Authors: Zahra Salehi, Bibi Fatemeh Nobakht Motlagh Ghoochani, Yazdan Hasani Nourian, Sadegh Azimzadeh Jamalkandi and Mostafa Ghanei
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:49
  39. Hereditary angioedema (HAE) is a rare disease characterized by unpredictable, recurring subcutaneous or submucosal swelling. Without effective therapy, HAE can negatively impact patients’ quality of life. Mana...

    Authors: Joan Mendivil, Maral DerSarkissian, Aleena Banerji, Lavanya Diwakar, Constance H. Katelaris, Paul K. Keith, Harold Kim, Gina Lacuesta, Markus Magerl, Charlotte Slade, William B. Smith, Zia Choudhry, Angela Simon, Sujata P. Sarda and Paula J. Busse
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:48
  40. Children with food allergy, and their families experience substantial burdens because of efforts necessary to minimize the risk of anaphylaxis. To this end, peer-to-peer education is paramount. Food Allergy Ca...

    Authors: Ranjit Dhanjal, Kyle Dine, Jennifer Gerdts, Kaitlyn Merrill, Tara Lynn M Frykas and Jennifer LP Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:47
  41. To validate case definitions for eczema using primary care Electronic Medical Record (EMR) data from the Canadian Primary Care Sentential Surveillance Network (CPCSSN).

    Authors: Hannah Stirton, Leanne Kosowan, Elissa M Abrams, Jennifer LP Protudjer, John Queenan and Alexander Singer
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:46

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