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  1. Up to 30% of patients with food allergies have clinical reactivity to more than one food allergen. Although there is currently no cure, oral immunotherapy (OIT) is under investigation. Pilot data have shown th...

    Authors: Philippe Bégin, Tina Dominguez, Shruti P Wilson, Liane Bacal, Anjuli Mehrotra, Bethany Kausch, Anthony Trela, Morvarid Tavassoli, Elisabeth Hoyte, Gerri O’Riordan, Alanna Blakemore, Scott Seki, Robert G Hamilton and Kari C Nadeau
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:7
  2. Wheat is one of the most common food allergens in children. The purpose of this study is to define the natural course of wheat allergy in children with dominant gastrointestinal symptoms and identify factors t...

    Authors: Grażyna Czaja-Bulsa and Michał Bulsa
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:12
  3. Home based oral immunotherapy (OIT) for food allergy has often been used for young children in Japan, the majority of whom are believed to outgrow the allergy by the school age, therefore the true efficacy of ...

    Authors: Kyoko Sudo, Shoichiro Taniuchi, Masaya Takahashi, Kazuhiko Soejima, Yasuko Hatano, Keiji Nakano, Tomohiko Shimo, Hayato Koshino and Kazunari Kaneko
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:11
  4. Bjerkandera adusta (B. adusta) is one of the most important etiological fungi associated with chronic cough. However, precise details of the inflammatory response to exposure are not well understood yet. B. adust...

    Authors: Boying Liu, Takamichi Ichinose, Miao He, Fumihisa Kobayashi, Teruya Maki, Seiichi Yoshida, Yasuhiro Yoshida, Keiichi Arashidani, Hirohisa Takano, Masataka Nishikawa, Guifan Sun and Takayuki Shibamoto
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:10
  5. Beta-hemolytic Group A Streptococcus invasive disease (iGASd) has been subject to intense research since its re-emergence in the late 1980s. In Quebec, an increase in the number of severe iGASd cases has recen...

    Authors: Isabel Fernandez, Rose-Marie Brito, Philippe Bidet, Fabien Rallu, Celine Laferrière, Philippe Ovetchkine and Francoise Le Deist
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:9
  6. Asthma is caused by both environmental and genetic factors. The ADRB2 gene, which encodes the beta 2-adrenergic receptor, is one of the most extensively studied genes with respect to asthma prevalence and severit...

    Authors: Ana Carolina Zimiani de Paiva, Fernando Augusto de Lima Marson, José Dirceu Ribeiro and Carmen Sílvia Bertuzzo
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:8
  7. The editors of Allergy Asthma & Clinical Immunology would like to thank all of our reviewers who have contributed to the journal in Volume 9 (2013).

    Authors: Richard Warrington
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:5
  8. Anaphylaxis, a form of IgE mediated hypersensitivity, arises when mast cells and possibly basophils are provoked to secrete mediators with potent vasoactive and smooth muscle contractile activities that evoke ...

    Authors: Roian Bayat and Rozita Borici-Mazi
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:6
  9. The aim of the study was to elucidate whether leukotriene receptor antagonists (LTRAs) can prevent severe allergic reactions, which occur during oral immunotherapy (OIT) in children with food allergies.

    Authors: Masaya Takahashi, Shoichiro Taniuchi, Kazuhiko Soejima, Kyoko Sudo, Yasuko Hatano and Kazunari Kaneko
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:3
  10. Thirty percent of children with food allergy are allergic to more than one food. Previous studies on oral immunotherapy (OIT) for food allergy have focused on the administration of a single allergen at the tim...

    Authors: Philippe Bégin, Lisa C Winterroth, Tina Dominguez, Shruti P Wilson, Liane Bacal, Anjuli Mehrotra, Bethany Kausch, Anthony Trela, Elisabeth Hoyte, Gerri O’Riordan, Scott Seki, Alanna Blakemore, Margie Woch, Robert G Hamilton and Kari C Nadeau
    Citation: Allergy, Asthma & Clinical Immunology 2014 10:1

    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2016 12:28

  11. While primary immunodeficiencies (PID has been recognized in the west for decades, recognition has been delayed in the third world. This study attempts to detail the spectrum of PID, the therapy provided, and ...

    Authors: Nilhan Rajiva de Silva, Sepali Gunawardena, Damayanthi Rathnayake and Geethani Devika Wickramasingha
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:50
  12. Post-hospital syndrome refers to the period of generalized risk of adverse health outcomes among patients who are recently discharged from hospital. This period is associated with a short-term increased risk o...

    Authors: Mohsen Sadatsafavi, Larry D Lynd and J Mark FitzGerald
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:49
  13. Staphylococcal enterotoxins may influence the pro-inflammatory pattern of chronic sinus diseases via epigenetic events. This work intended to investigate the potential of staphylococcal enterotoxin B (SEB) to ind...

    Authors: Claudina A Pérez-Novo, Yuan Zhang, Simon Denil, Geert Trooskens, Tim De Meyer, Wim Van Criekinge, Paul Van Cauwenberge, Luo Zhang and Claus Bachert
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:48
  14. Oral corticosteroids (OCS) are commonly administered in patients with severe persistent allergic asthma. Despite their efficacy, they are associated with a wide variety of adverse events. The eXpeRience regist...

    Authors: Gert-Jan Braunstahl, Jan Chlumský, Guy Peachey and Chien-Wei Chen
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:47
  15. In patients with asthma, medication adherence is a voluntary behavior that can be affected by numerous factors. Depression is an important co-morbidity in adolescents with asthma that may significantly impact ...

    Authors: Lokesh Guglani, Suzanne L Havstad, Dennis R Ownby, Jacquelyn Saltzgaber, Dayna A Johnson, Christine C Johnson and Christine LM Joseph
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:45
  16. Studies of avoidance of exposure to group 1 allergens of the Dermatophagoides group (Der p 1) have not yielded consistent improvements in adult asthma through avoidance. We explored whether the use of pillow and ...

    Authors: Naomi Tsurikisawa, Akemi Saito, Chiyako Oshikata, Takuya Nakazawa, Hiroshi Yasueda and Kazuo Akiyama
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:44
  17. Platelet-activating factor (PAF) is produced by most inflammatory cells and it is involved in inflammatory and allergic reactions. We aimed to assess the anti-PAF effects of rupatadine and levocetirizine in th...

    Authors: Rosa Muñoz-Cano, Antonio Valero, Ignacio Izquierdo, Jaume Sánchez-López, Alejandro Doménech, Joan Bartra, Joaquim Mullol and Cesar Picado
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:43
  18. Several different criteria for the positivity of the flow-assisted Basophil Activation Test (BAT) for the diagnosis of Neuromuscular Blocking Agents (NMBA) hypersensitivity reactions have been used in past stu...

    Authors: Natalia Hagau, Nadia Gherman-Ionica, Manuela Sfichi and Cristina Petrisor
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:42
  19. Airway remodeling is not specifically targeted by current asthma medications, partly owing to the lack of understanding of remodeling mechanisms, altogether posing great challenges in asthma treatment. Increas...

    Authors: Naresh Singh Redhu, Lianyu Shan, Duaa Al-Subait, Heather L Ashdown, Hesam Movassagh, Bouchaib Lamkhioued and Abdelilah S Gounni
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:41
  20. Basophils are important effectors cells in allergic rhinitis (AR) since they are involved in immunoglobulin (Ig) E – mediated inflammation and in the release of pro-inflammatory mediators. Specific subcutaneou...

    Authors: Ana Lopes, Patrícia Azenha, Cristina Teodósio, Maria Inácio, Isabel Silva, Graça Loureiro, António Martinho, António S Luís, Hélder Trindade, Celso Pereira and Artur Paiva
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:40
  21. There are few treatment options for patients with severe atopic asthma. Antagonism of IgE is an effective strategy. We investigated, by utilizing serum samples from a clinical trial of Rituximab in patients wi...

    Authors: Angira Dasgupta, Katherine Radford, Donald M Arnold, Lehana Thabane and Parameswaran Nair
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:39
  22. Atopic asthma is characterized by intermittent exacerbations triggered by exposure to allergen. Exacerbations are characterized by an acute inflammatory reaction in the airways, with recruitment of both innate...

    Authors: Jonathan S Boomer, Amit D Parulekar, Brenda M Patterson, Huiqing Yin-Declue, Christine M Deppong, Seth Crockford, Nizar N Jarjour, Mario Castro and Jonathan M Green
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:37
  23. We describe the first case of a patient with factitious disorder who closely simulated a primary immune deficiency disorder – Common Variable Immune Deficiency (CVID), by surreptitiously ingesting non-steroida...

    Authors: Rohan Ameratunga, Paul Casey, Susan Parry and Chris Kenedi
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:36
  24. The eliciting dose (ED) for a peanut allergic reaction in 5% of the peanut allergic population, the ED05, is 1.5 mg of peanut protein. This ED05 was derived from oral food challenges (OFC) that use graded, inc...

    Authors: Giovanni A Zurzolo, Katrina J Allen, Steve L Taylor, Wayne G Shreffler, Joseph L Baumert, Mimi L K Tang, Lyle C Gurrin, Michael L Mathai, Julie A Nordlee, Audrey DunnGalvin and Jonathan O’B Hourihane
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:35
  25. Referring to individuals with reactivity to honey bee and Vespula venom in diagnostic tests, the umbrella terms “double sensitization” or “double positivity” cover patients with true clinical double allergy and t...

    Authors: Johanna Stoevesandt, Bernd Hofmann, Johannes Hain, Andreas Kerstan and Axel Trautmann
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:33
  26. Since barrier protection measures to avoid contact with allergens are being increasingly developed, we assessed the clinical efficacy and tolerability of a topical nasal microemulsion made of glycerol esters i...

    Authors: Pedro Ojeda, Núria Piqué, Alicia Alonso, Julio Delgado, Francisco Feo, Juan Manuel Igea, Ana Navarro, José María Olaguibel, Javier Subiza, Carles Nieto and Morgan Andersson
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:32
  27. There is a lack of objective measures of the clinical efficacy of allergen immunotherapy which relies on patients’ perception about the effect of this treatment. We studied whether the fraction of exhaled nitr...

    Authors: Michele Columbo, Bruce Wong, Reynold A Panettieri Jr and Albert S Rohr
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:31
  28. Systemic corticosteroids play an integral role in the management of many inflammatory and immunologic conditions, but these agents are also associated with serious risks. Osteoporosis, adrenal suppression, hyp...

    Authors: Dora Liu, Alexandra Ahmet, Leanne Ward, Preetha Krishnamoorthy, Efrem D Mandelcorn, Richard Leigh, Jacques P Brown, Albert Cohen and Harold Kim
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:30
  29. Hereditary angioedema (HAE) is a rare, debilitating, and potentially life-threatening disease characterized by recurrent edema attacks. Important advances in HAE treatment have been made, including the develop...

    Authors: Andrea Zanichelli, Markus Magerl, Hilary Longhurst, Vincent Fabien and Marcus Maurer
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:29
  30. Oral corticosteroid prescriptions are often used in clinical studies as an indicator of asthma exacerbations. However, there is rarely the ability to link a prescription to its associated diagnosis. The object...

    Authors: Felicia C Allen-Ramey, Linda M Nelsen, Joseph B Leader, Dione Mercer, Henry Lester Kirchner and James B Jones
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:27
  31. The first documented confirmed case of an imported fire ant causing anaphylaxis in Canada is herein reported. In a patient with anaphylaxis to ants a physician in Canada should be aware that an allergic reacti...

    Authors: Jason Kihyuk Lee and Stephen Daniel Betschel
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:25
  32. Atopic dermatitis (AD) is a condition frequently encountered in medical practices across the country. Arming ourselves with appropriate and safe treatment modalities to provide relief for this chronic and rela...

    Authors: Audrey O Segal, Anne K Ellis and Harold L Kim
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:24
  33. A T helper cell (TH) 17-biased response has been observed in patients with allergic asthma, particularly in those with neutrophil accumulation in the lung. Therefore, we sought to test the hypothesis that neutrop...

    Authors: Carlos Ramirez-Velazquez, Elena Cristina Castillo, Leopoldo Guido-Bayardo and Vianney Ortiz-Navarrete
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:23
  34. Diagnostic testing to antibiotics other than to penicillin has not been widely available, making the diagnosis of antibiotic allergy difficult and often erroneous. There is often reluctance in performing chall...

    Authors: Fotini D Kavadas, Anna Kasprzak and Adelle R Atkinson
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:22
  35. Allergen-specific immunotherapy has been demonstrated to have potential for the treatment of allergic diseases. Transgenic animals are currently the best available bioreactors to produce recombinant proteins, ...

    Authors: Hsu-Chung Liu, Shun-Yuan Pai, Winston TK Cheng, Hsiao-Ling Chen, Tung-Chou Tsai, Shang-Hsun Yang and Chuan-Mu Chen
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:21
  36. Studies on time trends of allergic sensitization among adults are rare. The aim of the study was to compare the prevalence of allergic sensitization to common airborne allergens among adults 15 years apart and...

    Authors: Katja Warm, Anne Lindberg, Bo Lundbäck and Eva Rönmark
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:20
  37. Atmospheric contamination caused by Asian sand-dust (ASD) storms aggravates asthma in both human adults and children. This study aims to investigate a series of manifestations in allergic airway disease caused...

    Authors: Miao He, Takamichi Ichinose, Seiichi Yoshida, Hirohisa Takano, Masataka Nishikawa, Guifan Sun and Takayuki Shibamoto
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:19
  38. Insufficient knowledge of food allergy and anaphylaxis has been identified by caregivers as an important barrier to coping, and a potential cause of fear and anxiety, particularly for those with children newly...

    Authors: Zainab B Abdurrahman, Monika Kastner, Cory Wurman, Laurie Harada, Laura Bantock, Heather Cruickshank and Susan Waserman
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:18

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