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  1. Azelastine has been shown to be effective against seasonal allergic rhinitis (SAR). The Environmental Exposure Unit (EEU) is a validated model of experimental SAR. The objective of this double-blind, four-way ...

    Authors: Anne K Ellis, Yifei Zhu, Lisa M Steacy, Terry Walker and James H Day
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:16
    Content type: Research Published on:

  2. Multiple studies have demonstrated that early-life exposure to pets or siblings affords protection against allergic disease; these associations are commonly attributed to the “hygiene hypothesis”. Recently, lo...

    Authors: Meghan B Azad, Theodore Konya, Heather Maughan, David S Guttman, Catherine J Field, Malcolm R Sears, Allan B Becker, James A Scott and Anita L Kozyrskyj
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:15
    Content type: Research Published on:

  3. Mode of delivery may affect the risk of asthma but the findings have not been consistent and factors shared by siblings may confound the associations in previous studies.

    Authors: Lennart Bråbäck, Cecilia Ekéus, Adrian J Lowe and Anders Hjern
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:14
    Content type: Research Published on:

  4. Helminth infections and allergies are associated with TH2 responses. Whereas the development of TH2 responses and allergic disorders in pediatric populations has been examined in affluent countries, no or little ...

    Authors: Yenny Djuardi, Taniawati Supali, Heri Wibowo, Yvonne CM Kruize, Serge A Versteeg, Ronald van Ree, Erliyani Sartono and Maria Yazdanbakhsh
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:13
    Content type: Research Published on:

  5. Drug provocation tests (DPTs) are often needed when evaluating patients with suspected drug hypersensitivity reactions. General considerations on DPTs, with regard to indications, contraindications, methods, l...

    Authors: Anca Mirela Chiriac and Pascal Demoly
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:12
    Content type: Review Published on:

  6. The editors of Allergy, Asthma & Clinical Immunology would like to thank all of our reviewers who have contributed to the journal in Volume 8 (2012).

    Authors: Richard Warrington
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:3
    Content type: Reviewer acknowledgement Published on:

  7. We present two cases of food and exercise-induced anaphylaxis (FEIA) in patients with a diagnosis of oral allergy syndrome (OAS) to the implicated foods. Patient A had FEIA attributed to fresh coriander and to...

    Authors: Jennifer Yan Fei Chen, Jaclyn Quirt and Kihyuk Jason Lee
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:11
    Content type: Case report Published on:

  8. The aetiology of childhood asthma is complex. An early dysfunction in the immunological development of the innate immune system in combination with environmental factors possibly triggers asthma. CD14 and toll...

    Authors: Ester MM Klaassen, Brenda EJT Thönissen, Guillaume van Eys, Edward Dompeling and Quirijn Jöbsis
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:10
    Content type: Review Published on:

  10. Uncontrolled asthma remains a frequent cause of emergency department (ED) visits and hospital admissions. Improper asthma inhaler device use is most likely one of the major causes associated with uncontrolled ...

    Authors: Hamdan AL-Jahdali, Anwar Ahmed, Abdullah AL-Harbi, Mohd Khan, Salim Baharoon, Salih Bin Salih, Rabih Halwani and Saleh Al-Muhsen
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:8
    Content type: Research Published on:

  11. A diagnosis of peanut allergy has a major impact on an individual’s quality of life. Exposure to even small amounts of peanut can trigger serious reactions. Common cleaning agents can easily remove peanut alle...

    Authors: Wade TA Watson, AnnMarie Woodrow and Andrew W Stadnyk
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:7
    Content type: Research Published on:

  13. While a growing body of research is uncovering the aetiology and effective treatments for allergy, research that assess the broader ethical implications of this disease is lacking significantly. This article w...

    Authors: Jason Behrmann
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:5
    Content type: Review Published on:

  14. The gene ORMDL3 was shown to be associated with early-onset asthma susceptibility in multiple independent genome-wide and candidate-gene association studies. Asthmatic patients have elevated expression levels of ...

    Authors: Karolynn J Hsu and Stuart E Turvey
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:4
    Content type: Research Published on:

  15. Immunostimulatory therapy is now being recognized as an alternative to conventional chemotherapy for a variety of disease conditions, involving the impaired immune response of the host. In the present study, t...

    Authors: Assia Benmebarek, Sakina Zerizer, Souheila Laggoune and Zahia Kabouche
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:2
    Content type: Research Published on:

  16. Heparins are one of the most used class of anticoagulants in daily clinical practice. Despite their widespread application immune-mediated hypersensitivity reactions to heparins are rare. Among these, the dela...

    Authors: Diana Anders and Axel Trautmann
    Citation: Allergy, Asthma & Clinical Immunology 2013 9:1
    Content type: Case report Published on:

  17. Anti-neutrophil cytoplasmic antibodies are typically detected in anti-neutrophil cytoplasmic antibody associated vasculitis, but are also present in a number of chronic inflammatory non-vasculitic conditions l...

    Authors: David Spoerl, Yves-Marie Pers and Christian Jorgensen
    Citation: Allergy, Asthma & Clinical Immunology 2012 8:19
    Content type: Case report Published on:

  18. In this work we explore differences in blood cells and cytokine profiles in children according to atopic status and asthma (atopic or non-atopic). The study involved measurement of Th1(IFN-γ) and Th2 (IL-5 and...

    Authors: Camila Alexandrina Figueiredo, Laura Cunha Rodrigues, Neuza Maria Alcantara-Neves, Philip J Cooper, Leila Denise Amorim, Nivea Bispo Silva, Alvaro A Cruz and Mauricio Lima Barreto
    Citation: Allergy, Asthma & Clinical Immunology 2012 8:18
    Content type: Letter to the editor Published on:

  19. A seasonal effect of month of birth and risk of allergic disease has been suggested by numerous studies. Few studies have directly measured pollen exposures at different points during pregnancy and in early li...

    Authors: Adrian J Lowe, David Olsson, Lennart Bråbäck and Bertil Forsberg
    Citation: Allergy, Asthma & Clinical Immunology 2012 8:17
    Content type: Research Published on:

  48. The immunological and clinical parameters that are associated with asthma remission are poorly understood. The cytokine and local mediator changes associated with the resolution of asthma symptoms were examine...

    Authors: Susan Waserman, Parameswaran Nair, Denis Snider, Mary Conway, Lata Jayaram, Lynn M McCleary, Jerry Dolovich, Frederick E Hargreave and Jean S Marshall
    Citation: Allergy, Asthma & Clinical Immunology 2012 8:16
    Content type: Research Published on:

  49. Allergy to peanuts results in severe anaphylactic responses in affected individuals, and has dramatic effects on society and public policy. Despite the health impacts of peanut-induced anaphylaxis (PIA), relat...

    Authors: Steven Maltby, Erin J DeBruin, Jami Bennett, Matthew J Gold, Matthew C Tunis, Zhiqi Jian, Jean S Marshall and Kelly M McNagny
    Citation: Allergy, Asthma & Clinical Immunology 2012 8:15
    Content type: Research Published on:

  50. Presenting processed antigens to CD4+ lymphocytes during the immune response involves major histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription fa...

    Authors: Réda Djidjik, Nesrine Messaoudani, Azzedine Tahiat, Yanis Meddour, Samia Chaib, Aziz Atek, Mohammed Elmokhtar Khiari, Nafissa Keltoum Benhalla, Leila Smati, Abdelatif Bensenouci, Mourad Baghriche and Mohammed Ghaffor
    Citation: Allergy, Asthma & Clinical Immunology 2012 8:14
    Content type: Research Published on:

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