The official journal of CSACI
Articles
Page 21 of 29
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Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A72
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Systematic review of outcome measures in randomised controlled trials of pediatric eosinophilic esophagitis (EoE) treatment
Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A70 -
Evaluating preferences for long term wheeze following RSV infection using TTO and best-worst scaling
Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A64 -
Estimating the impact of temperature and air pollution on cardiopulmonary and diabetic health during the TORONTO 2015 Pan Am/Parapan Am Games
Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A62 -
Infant gut microbiota and the development of wheeze in early childhood
Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A35 -
Impact of perinatal antibiotic exposure on the infant gut microbiota at one year of age
Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A31 -
Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: a systematic review and meta-analysis
Citation: Allergy, Asthma & Clinical Immunology 2014 10(Suppl 1):A25 -
Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab
Up to 30% of patients with food allergies have clinical reactivity to more than one food allergen. Although there is currently no cure, oral immunotherapy (OIT) is under investigation. Pilot data have shown th...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:7 -
The natural history of IgE mediated wheat allergy in children with dominant gastrointestinal symptoms
Wheat is one of the most common food allergens in children. The purpose of this study is to define the natural course of wheat allergy in children with dominant gastrointestinal symptoms and identify factors t...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:12 -
Home-based oral immunotherapy (OIT) with an intermittent loading protocol in children unlikely to outgrow egg allergy
Home based oral immunotherapy (OIT) for food allergy has often been used for young children in Japan, the majority of whom are believed to outgrow the allergy by the school age, therefore the true efficacy of ...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:11 -
Lung inflammation by fungus, Bjerkandera adusta isolated from Asian sand dust (ASD) aerosol and enhancement of ovalbumin-induced lung eosinophilia by ASD and the fungus in mice
Bjerkandera adusta (B. adusta) is one of the most important etiological fungi associated with chronic cough. However, precise details of the inflammatory response to exposure are not well understood yet. B. adust...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:10 -
Invasive group A Streptococcus disease in French-Canadian children is not associated with a defect in MyD88/IRAK4-pathway
Beta-hemolytic Group A Streptococcus invasive disease (iGASd) has been subject to intense research since its re-emergence in the late 1980s. In Quebec, an increase in the number of severe iGASd cases has recen...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:9 -
Asthma: Gln27Glu and Arg16Gly polymorphisms of the beta2-adrenergic receptor gene as risk factors
Asthma is caused by both environmental and genetic factors. The ADRB2 gene, which encodes the beta 2-adrenergic receptor, is one of the most extensively studied genes with respect to asthma prevalence and severit...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:8 -
Reviewer acknowledgement 2013
The editors of Allergy Asthma & Clinical Immunology would like to thank all of our reviewers who have contributed to the journal in Volume 9 (2013).
Citation: Allergy, Asthma & Clinical Immunology 2014 10:5 -
A case of anaphylaxis to peppermint
Anaphylaxis, a form of IgE mediated hypersensitivity, arises when mast cells and possibly basophils are provoked to secrete mediators with potent vasoactive and smooth muscle contractile activities that evoke ...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:6 -
Aluminium adjuvants and adverse events in sub-cutaneous allergy immunotherapy
Sub-cutaneous immunotherapy is an effective treatment for allergy. It works by helping to modify or re-balance an individual’s immune response to allergens and its efficacy is greatly improved by the use of ad...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:4 -
New efficacy of LTRAs (montelukast sodium): it possibly prevents food-induced abdominal symptoms during oral immunotherapy
The aim of the study was to elucidate whether leukotriene receptor antagonists (LTRAs) can prevent severe allergic reactions, which occur during oral immunotherapy (OIT) in children with food allergies.
Citation: Allergy, Asthma & Clinical Immunology 2014 10:3 -
T cell unresponsiveness in a pediatric cystic fibrosis patient: a case report
A girl was diagnosed with cystic fibrosis (CF) at birth, with repeatedly positive sweat tests and homozygous F508del mutations of her CF transmembrane conductance regulator (CFTR) gene. From an early age, her lun...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:2 -
Safety and feasibility of oral immunotherapy to multiple allergens for food allergy
Thirty percent of children with food allergy are allergic to more than one food. Previous studies on oral immunotherapy (OIT) for food allergy have focused on the administration of a single allergen at the tim...
Citation: Allergy, Asthma & Clinical Immunology 2014 10:1 -
Spectrum of primary immunodeficiency disorders in Sri Lanka
While primary immunodeficiencies (PID has been recognized in the west for decades, recognition has been delayed in the third world. This study attempts to detail the spectrum of PID, the therapy provided, and ...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:50 -
Post-hospital syndrome in adults with asthma: a case-crossover study
Post-hospital syndrome refers to the period of generalized risk of adverse health outcomes among patients who are recently discharged from hospital. This period is associated with a short-term increased risk o...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:49 -
Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue: a preliminary study
Staphylococcal enterotoxins may influence the pro-inflammatory pattern of chronic sinus diseases via epigenetic events. This work intended to investigate the potential of staphylococcal enterotoxin B (SEB) to ind...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:48 -
Reduction in oral corticosteroid use in patients receiving omalizumab for allergic asthma in the real-world setting
Oral corticosteroids (OCS) are commonly administered in patients with severe persistent allergic asthma. Despite their efficacy, they are associated with a wide variety of adverse events. The eXpeRience regist...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:47 -
Vitamin C and common cold-induced asthma: a systematic review and statistical analysis
Asthma exacerbations are often induced by the common cold, which, in turn, can be alleviated by vitamin C.
Citation: Allergy, Asthma & Clinical Immunology 2013 9:46 -
Exploring the impact of elevated depressive symptoms on the ability of a tailored asthma intervention to improve medication adherence among urban adolescents with asthma
In patients with asthma, medication adherence is a voluntary behavior that can be affected by numerous factors. Depression is an important co-morbidity in adolescents with asthma that may significantly impact ...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:45 -
Encasing bedding in covers made of microfine fibers reduces exposure to house mite allergens and improves disease management in adult atopic asthmatics
Studies of avoidance of exposure to group 1 allergens of the Dermatophagoides group (Der p 1) have not yielded consistent improvements in adult asthma through avoidance. We explored whether the use of pillow and ...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:44 -
Evaluation of nasal symptoms induced by platelet activating factor, after nasal challenge in both healthy and allergic rhinitis subjects pretreated with rupatadine, levocetirizine or placebo in a cross-over study design
Platelet-activating factor (PAF) is produced by most inflammatory cells and it is involved in inflammatory and allergic reactions. We aimed to assess the anti-PAF effects of rupatadine and levocetirizine in th...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:43 -
Threshold for basophil activation test positivity in neuromuscular blocking agents hypersensitivity reactions
Several different criteria for the positivity of the flow-assisted Basophil Activation Test (BAT) for the diagnosis of Neuromuscular Blocking Agents (NMBA) hypersensitivity reactions have been used in past stu...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:42 -
IgE induces proliferation in human airway smooth muscle cells: role of MAPK and STAT3 pathways
Airway remodeling is not specifically targeted by current asthma medications, partly owing to the lack of understanding of remodeling mechanisms, altogether posing great challenges in asthma treatment. Increas...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:41 -
Impact of allergic rhinitis and specific subcutaneous immunotherapy on peripheral blood basophils of patients sensitized to Dermatophagoides pteronyssinus
Basophils are important effectors cells in allergic rhinitis (AR) since they are involved in immunoglobulin (Ig) E – mediated inflammation and in the release of pro-inflammatory mediators. Specific subcutaneou...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:40 -
The effects of rituximab on serum IgE and BAFF
There are few treatment options for patients with severe atopic asthma. Antagonism of IgE is an effective strategy. We investigated, by utilizing serum samples from a clinical trial of Rituximab in patients wi...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:39 -
The utility of using fiberoptic rhinoscopy in the diagnosis of nasal polyps
Symtomatology of nasal polyps (NP) is relatively non-specific and other nasal conditions that cause nasal may be mistaken for NP. The purpose of this study was to evaluate the accuracy otoscopic (OT) examinati...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:38 -
A detailed phenotypic analysis of immune cell populations in the bronchoalveolar lavage fluid of atopic asthmatics after segmental allergen challenge
Atopic asthma is characterized by intermittent exacerbations triggered by exposure to allergen. Exacerbations are characterized by an acute inflammatory reaction in the airways, with recruitment of both innate...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:37 -
Hypogammaglobulinemia factitia- Munchausen syndrome masquerading as common variable immune deficiency
We describe the first case of a patient with factitious disorder who closely simulated a primary immune deficiency disorder – Common Variable Immune Deficiency (CVID), by surreptitiously ingesting non-steroida...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:36 -
Peanut Allergen Threshold Study (PATS): validation of eliciting doses using a novel single-dose challenge protocol
The eliciting dose (ED) for a peanut allergic reaction in 5% of the peanut allergic population, the ED05, is 1.5 mg of peanut protein. This ED05 was derived from oral food challenges (OFC) that use graded, inc...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:35 -
Erratum to: Predictive value of IgE/IgG4 antibody ratio in children with egg allergy
Citation: Allergy, Asthma & Clinical Immunology 2013 9:34 -
Single venom-based immunotherapy effectively protects patients with double positive tests to honey bee and Vespula venom
Referring to individuals with reactivity to honey bee and Vespula venom in diagnostic tests, the umbrella terms “double sensitization” or “double positivity” cover patients with true clinical double allergy and t...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:33 -
A topical microemulsion for the prevention of allergic rhinitis symptoms: results of a randomized, controlled, double-blind, parallel group, multicentre, multinational clinical trial (Nares study)
Since barrier protection measures to avoid contact with allergens are being increasingly developed, we assessed the clinical efficacy and tolerability of a topical nasal microemulsion made of glycerol esters i...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:32 -
The effect of multiple allergen immunotherapy on exhaled nitric oxide in adults with allergic rhinitis
There is a lack of objective measures of the clinical efficacy of allergen immunotherapy which relies on patients’ perception about the effect of this treatment. We studied whether the fraction of exhaled nitr...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:31 -
A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy
Systemic corticosteroids play an integral role in the management of many inflammatory and immunologic conditions, but these agents are also associated with serious risks. Osteoporosis, adrenal suppression, hyp...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:30 -
Hereditary angioedema with C1 inhibitor deficiency: delay in diagnosis in Europe
Hereditary angioedema (HAE) is a rare, debilitating, and potentially life-threatening disease characterized by recurrent edema attacks. Important advances in HAE treatment have been made, including the develop...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:29 -
Retraction Note: Severe contact dermatitis due to camomile: a common complementary remedy with potential sensitization risks
Citation: Allergy, Asthma & Clinical Immunology 2013 9:28 -
Electronic health record-based assessment of oral corticosteroid use in a population of primary care patients with asthma: an observational study
Oral corticosteroid prescriptions are often used in clinical studies as an indicator of asthma exacerbations. However, there is rarely the ability to link a prescription to its associated diagnosis. The object...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:27 -
Article removed: Severe contact dermatitis due to camomile: a common complementary remedy with potential sensitization risks
Citation: Allergy, Asthma & Clinical Immunology 2013 9:26 -
A case of the first documented fire ant anaphylaxis in Canada
The first documented confirmed case of an imported fire ant causing anaphylaxis in Canada is herein reported. In a patient with anaphylaxis to ants a physician in Canada should be aware that an allergic reacti...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:25 -
CSACI position statement: safety of topical calcineurin inhibitors in the management of atopic dermatitis in children and adults
Atopic dermatitis (AD) is a condition frequently encountered in medical practices across the country. Arming ourselves with appropriate and safe treatment modalities to provide relief for this chronic and rela...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:24 -
IL-17-producing peripheral blood CD177+ neutrophils increase in allergic asthmatic subjects
A T helper cell (TH) 17-biased response has been observed in patients with allergic asthma, particularly in those with neutrophil accumulation in the lung. Therefore, we sought to test the hypothesis that neutrop...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:23 -
Antibiotic skin testing accompanied by provocative challenges in children is a useful clinical tool
Diagnostic testing to antibiotics other than to penicillin has not been widely available, making the diagnosis of antibiotic allergy difficult and often erroneous. There is often reluctance in performing chall...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:22 -
Ingestion of milk containing the Dp2 peptide, a dust mite allergen, protects mice from allergic airway inflammation and hyper-responsiveness
Allergen-specific immunotherapy has been demonstrated to have potential for the treatment of allergic diseases. Transgenic animals are currently the best available bioreactors to produce recombinant proteins, ...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:21 -
Increase in sensitization to common airborne allergens among adults – two population-based studies 15 years apart
Studies on time trends of allergic sensitization among adults are rare. The aim of the study was to compare the prevalence of allergic sensitization to common airborne allergens among adults 15 years apart and...
Citation: Allergy, Asthma & Clinical Immunology 2013 9:20
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