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  1. Osteopontin (OPN) is a multifunctional cytokine that has been primarily investigated in Th1 diseases. Recently, it has also been implicated in Th2-mediated allergic diseases, such as asthma. The expression of ...

    Authors: Serena E O'Neil, Carina Malmhäll, Konstantinos Samitas, Teet Pullerits, Apostolos Bossios and Jan Lötvall

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:28

    Content type: Research

    Published on:

  2. Little information is available on the effect of allergen-specific immunotherapy on airway responsiveness and markers in exhaled air. The aims of this study were to assess the safety of immunotherapy with puri...

    Authors: Luis Prieto, Ricardo Palacios, Dulce Aldana, Anna Ferrer, Carmen Perez-Frances, Victoria Lopez and Rocio Rojas

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:27

    Content type: Research

    Published on:

  3. Eosinophilic esophagitis (EoE) is characterized by the inflammation of the esophagus and the infiltration of eosinophils into the esophagus, leading to symptoms such as dysphagia and stricture formation. Syste...

    Authors: Jennifer J Huang, Jae Won Joh, Judy Fuentebella, Anup Patel, Tammie Nguyen, Scott Seki, Lisa Hoyte, Neha Reshamwala, Christine Nguyen, Anthony Quiros, Dorsey Bass, Eric Sibley, William Berquist, Kenneth Cox, John Kerner and Kari C Nadeau

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:25

    Content type: Research

    Published on:

  4. We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angio...

    Authors: Tom Bowen, Marco Cicardi, Henriette Farkas, Konrad Bork, Hilary J Longhurst, Bruce Zuraw, Emel Aygoeren-Pürsün, Timothy Craig, Karen Binkley, Jacques Hebert, Bruce Ritchie, Laurence Bouillet, Stephen Betschel, Della Cogar, John Dean, Ramachand Devaraj…

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:24

    Content type: Review

    Published on:

  5. Advances in understanding the pathophysiology and mechanism of swelling in hereditary angioedema (HAE) has resulted in the development of multiple new drugs for the acute and prophylactic treatment of patients...

    Authors: Bruce L Zuraw

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:23

    Content type: Review

    Published on:

  6. Hereditary angioedema (C1 inhibitor deficiency, HAE) is associated with intermittent swellings which are disabling and may be fatal. Effective treatments are available and these are most useful when given earl...

    Authors: Hilary J Longhurst, Henriette Farkas, Timothy Craig, Emel Aygören-Pürsün, Claire Bethune, Janne Bjorkander, Konrad Bork, Laurence Bouillet, Henrik Boysen, Anette Bygum, Teresa Caballero, Marco Cicardi, John Dempster, Mark Gompels, Jimmy Gooi, Sofia Grigoriadou…

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:22

    Content type: Review

    Published on:

  7. Manifestation of acute edema in hereditary angioedema (HAE) is characterized by interindividual and intraindividual variability in symptom expression over time. Flexible therapy options are needed.

    Authors: Emel Aygören-Pürsün, Inmaculada Martinez-Saguer, Eva Rusicke, Thomas Klingebiel and Wolfhart Kreuz

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:21

    Content type: Research

    Published on:

  8. C1-inhibitor (C1-INH) deficiency is a rare blood disorder resulting in angioedema attacks that are debilitating and may be life-threatening. Prophylaxis and therapy of events has changed since our first Canadi...

    Authors: Tom Bowen, John Brosz, Kristylea Brosz, Jacques Hebert and Bruce Ritchie

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:20

    Content type: Research

    Published on:

  9. Women with hereditary angioedema (HAE) are more likely to be symptomatic that men. Hormonal factors (puberty, contraception, pregnancy,....) play a significant role in the precipitation or worsening of the con...

    Authors: Laurence Bouillet

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:17

    Content type: Review

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  10. Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released ...

    Authors: Marco Cicardi and Andrea Zanichelli

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:14

    Content type: Review

    Published on:

  11. Primary immune deficiency disorders (PIDs) are a group of diseases associated with a genetic predisposition to recurrent infections, malignancy, autoimmunity and allergy. The molecular basis of many of these d...

    Authors: Rohan Ameratunga, See-Tarn Woon, Katherine Neas and Donald R Love

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:12

    Content type: Review

    Published on:

  12. The current geriatric population in the United States accounts for approximately 12% of the total population and is projected to reach nearly 20% (71.5 million people) by 2030[1]. With this expansion of the numbe...

    Authors: Jayant M Pinto and Seema Jeswani

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:10

    Content type: Review

    Published on:

  13. T cell disorders have been poorly understood until recently. Lack of knowledge of underlying molecular mechanisms together with incomplete data on long term outcome have made it difficult to assess prognosis a...

    Authors: Theresa S Cole and Andrew J Cant

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:9

    Content type: Review

    Published on:

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