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Table 2 Clinical Indications for Allergen Immunotherapy

From: Update on Allergy Immunotherapy

Allergic rhinitis

Symptoms of allergic rhinitis with natural exposure to allergens, evidence of clinically relevant

IgE antibodies, and one of the following:

Poor response to pharmacotherapy or allergen avoidance

Unacceptable adverse effects of medications

Desire to avoid long-term pharmacotherapy and reduce the cost of medication

Coexisting allergic rhinitis and asthma

Possible prevention of asthma in children*

Allergic asthma

Symptoms of allergic asthma with natural exposure to aeroallergens, evidence of clinically relevant

IgE antibodies, and one of the following:

Poor response to pharmacotherapy or allergen avoidance*

Unacceptable adverse effects of medications*

Desire to avoid long-term pharmacotherapy and reduce the cost of medication*

Coexisting allergic rhinitis and asthma

  1. Adapted from Joint Task Force on Practice Parameters [5]; Canadian Society of Allergy and Clinical Immunology [1].
  2. IgE = immunoglobulin E.
  3. *Controversial (see text for discussion).