Basophil activation test compared to skin prick test and fluorescence enzyme immunoassay for aeroallergen-specific Immunoglobulin-E

Table 2 Correlation between SPT and BAT, SPT and FEIA, and BAT and FEIA results, and sensitivity* and specificity** of BAT and FEIA using SPT as the "gold standard".

	SPT vs BAT	SPT vs FEIA	BAT vs FEIA	BAT sensitivity	FEIA sensitivity	BAT specificity	FEIA specificity
Cat	R = .42 P < .001	R = .61 P < .001	R = .44 P < .001	.84	.84	.73	.83
Dog	R = .37 P = .001	R = .59 P < .001	R = .32 P = .007	.57	.64	.81	.92
DP	R = .38 P = .001	R = .42 P < .001	R = .33 P = .005	.63	.63	.76	.87
Timothy	R = .54 P < .001	R = .77 P < .001	R = .53 P < .001	.80	.80	.80	.82
Birch	R = .43 P < .001	R = .52 P < .001	R = .35 P = .003	.57	.61	.76	.93

* Calculated as the number of persons allergic for that allergen by both SPT and BAT or FEIA/total number of persons allergic for that allergen by SPT.
** Calculated as the number of persons nonallergic for that allergen by both SPT and BAT or FEIA/total number of persons nonallergic for that allergen by SPT. Persons nonallergic for that allergen by SPT included both asymptomatic persons with negative SPT for all 9 allergens as well as symptomatic persons with positive SPT for allergen(s) other than the allergen of interest.

ISSN: 1710-1492