Fig. 3
From: Clinical validation of controlled exposure to birch pollen in the Environmental Exposure Unit (EEU)
Increase in TNSS and TRSS reported by birch allergic participants during the EEU challenge visit. Birch allergic participants reported a gradual increase in total nasal symptom scores (TNSS) and total rhinoconjunctivitis symptom scores (TRSS), reaching a maximum of 7 and 11.6 respectively at 180 min, and sustaining this level until the end of the exposure period at 240 min. Symptoms gradually returned to near baseline values following the end of exposure. Non-allergic participants did not report such changes and had no statistically significant increase in scores from baseline