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Fig. 2 | Allergy, Asthma & Clinical Immunology

Fig. 2

From: Genetic and epigenetic studies of atopic dermatitis

Fig. 2

The schematic illustration of AD etiology. Genetic and epigenetic reasons lead to the alteration of gene expression and function of AD associated genes. AD associated genes majorly belong to two pathways: skin barrier and innate/adaptive immunity. Dysregulation of innate/adaptive immune responses and impaired skin barrier reciprocally affect each other to drive AD development

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