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Table 3 Response to pneumococcal vaccination in the overall cohort

From: A case series evaluating the serological response of adult asthma patients to the 23-valent pneumococcal polysaccharide vaccine

Pneumococcal serotype

Serum samples

Anti-CP GMC† (95% CI) (µg/mL)

Mean fold rise (95% CI)

6B

Baseline

0.54 (0.21–1.38)

–

Post-vaccination

2.13 (0.72–6.28)**

3.96 (1.70–9.22)

9V

Baseline

1.19 (0.64–2.22)

–

Post-vaccination

4.25 (2.19–8.24)***

3.57 (1.84–6.93)

19A

Baseline

7.78 (4.2–14.4)

–

Post-vaccination

15.34 (8.39–28.05)**

1.97 (1.26–3.09)

19F

Baseline

1.70 (0.64–4.56)

–

Post-vaccination

7.76 (3.26–18.46)***

4.56 (2.26–9.21)

23F

Baseline

0.94 (0.43–2.08)

–

Post-vaccination

3.81 (1.56–9.30)****

4.03 (2.35–6.92)

  1. † Anti-CP GMC anti-capsular polysaccharide geometric mean concentration
  2. ** p < 0.01, *** p < 0.001, **** p < 0.0001