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Table 1 Strasbourg diagnostic criteria

From: Therapy resistant urticaria as a long-term symptom of an incomplete Schnitzler syndrome

Obligate criteria

Minor criteria

Chronic recurring urticaria

Recurring fever

Monoclonal gammopathy (IgM or IgG)

Abnormal bone remodeling ± pain

 

Neutrophilic dermal infiltrate

 

leukocytosis and/or elevated CRP

  1. To diagnose the Schnitzler syndrome, according to the Strasbourg criteria, the two obligate criteria and at least 2 minor criteria must be present (with an IgM gammopathy; at least three minor criteria with an IgG gammopathy) [3]
  2. IgM Immunoglobulin M, IgG Immunoglobulin G, CRP C-reactive Protein
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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