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Table 3 Process of diagnosis

From: Therapy resistant urticaria as a long-term symptom of an incomplete Schnitzler syndrome

DATE

DIAGNOSIS

THERAPY

 

12/2013

Intolerance reaction (ACE-Inhibitors)

Corticosteroids, AH

Hives covering the whole body

03/2014

Chronic spontaneous urticaria

05/2014

AH

08/2014

Omalizumab

10/2014

AH

Augmented urticaria after meat consumption

06/2017

 

Urticaria pigmentosa (particularly trunk)

07/2017

Cutaneous mastocytosis—skin biopsy

AH, Corticosteroids (Azathioprin as MG therapy)

No local findings

04/2018

Cutaneous mastocytosis—bone marrow biopsy IgM MGUS DD CSU

AH

Augmented hives

05/2021

Omalizumab

Arthralgia and urticaria

11/2021

Omalizumab increased dose

Augmented hives

02/2022

Schnitzler syndrome

AH

Augmented hives after vaccination, recurring fever

03/2022

Anakinra

Recession of hives, reaction at injection site, Return of hives after therapy discontinuation

04/2022

Canakinumab

Complete remissions of symptoms

  1. Not all appointments at the physician are displayed
  2. ACE Angiotensin-converting enzyme, AH Antihistamines, MG Myasthenia gravis, DD Differential diagnosis, CSU chronic spontaneous urticaria