Fig. 2

Percent change in mean total IgE = Immunoglobulin E after ETI = Elexacaftor/Tezacaftor/Ivacaftor initiation in the A presence of fungus or B presence of MRSA = Methicillin Resistant Staphylococcus Aureus or C presence of MSSA or D presence of Pseudomonas, with 95% confidence intervals from the multivariable mixed- effect model. Each point represents the percent change in 12-month mean IgE of a single patient after starting ETI. p-values above each group denote the significance of the percent change for that group from no change, and p-values connecting groups denote the significance of the difference in percent change across groups