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Table 3 Factors associated with the absence of humoral immune response to the SARS-CoV-2 vaccination

From: Immune response after SARS-CoV-2 vaccination in patients with inflammatory immune-mediated diseases receiving immunosuppressive treatment

 

Univariate analysis

Multivariate analysis

OR

95% CI

OR

95% CI

Age

0.9

0.9–1.01

0.9

0.9–1.04

BMI

0.9

0.9–1.1

–

–

Rituximab use

34*

4.1–280.2*

24.7*

2.9–211.2*

Methotrexate use

1.3

0.4–4.3

–

–

Methotrexate dose (mg/week)

0.9

0.8–1.1

–

–

Prednisone use

4.2*

1.2–14*

2.2

0.5–9.3

Prednisone dose (mg/day)

0.9

0.6–1.3

0.3

0.1–1.9

  1. The univariate analysis revealed that sex, age, RA diagnosis, rituximab and prednisone use were associated with undetectable serum levels of anti-SARS-CoV-2 antibodies. However, the multivariate analysis only showed an association with rituximab use
  2. * Statistically signicant data are shown in bold. 
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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