Correlations between IL-36 family cytokines in peripheral blood and subjective and objective assessment results in patients with allergic rhinitis

Table 4 Correlation analysis of IL-36 family cytokine concentration levels with VAS scores and SNOT-22 score in peripheral blood of 77 patients with AR

Scoring items	IL-36α		IL-36β		IL-36γ		IL-36Ra		IL-38
Scoring items	r value	p value	r value	p value	r value	p value	r value	p value	r value	p value
Total VAS score for nasal symptoms	0.12	0.317	0.13	0.266	0.09	0.417	0.17	0.147	0.10	0.383
VAS score for nasal itching	0.00	0.996	0.11	0.360	-0.02	0.857	0.11	0.341	0.21	0.066
VAS score for sneezing	-0.10	0.401	-0.04	0.757	-0.05	0.693	0.00	0.983	-0.09	0.418
VAS score for runny nose	0.11	0.363	0.14	0.235	0.20	0.084	0.15	0.192	0.19	0.100
VAS score for nasal congestion	0.26	0.023	0.01	0.952	0.10	0.384	0.08	0.513	-0.11	0.333
Total VAS score for ocular symptoms	0.07	0.541	0.27	0.020	0.05	0.642	0.18	0.111	0.20	0.074
VAS score for ocular itching	0.04	0.746	0.25	0.028	-0.06	0.626	0.15	0.207	0.21	0.069
VAS score for lacrimation	0.04	0.715	0.12	0.299	0.08	0.502	0.06	0.624	0.10	0.370
VAS score for eye redness	0.04	0.732	0.13	0.276	0.06	0.611	0.20	0.084	0.00	0.999
VAS score for eye pain	0.12	0.280	0.24	0.034	0.02	0.849	0.14	0.216	0.18	0.120
Total VAS score for asthma-related symptoms	0.11	0.335	0.09	0.459	0.01	0.954	-0.09	0.445	0.00	0.994
VAS score for cough	0.21	0.068	0.12	0.299	0.03	0.794	-0.02	0.874	0.03	0.799
VAS score for suffocation	0.09	0.450	-0.05	0.677	0.20	0.088	-0.14	0.241	-0.03	0.807
VAS score for wheezing	-0.01	0.922	0.02	0.893	0.01	0.898	-0.06	0.575	-0.07	0.573
VAS score for squeezing	-0.10	0.409	0.14	0.241	-0.08	0.482	-0.03	0.798	0.07	0.530
SNOT-22 score	0.11	0.327	0.02	0.890	0.08	0.488	-0.06	0.624	-0.12	0.308

IL interleukin, VAS visual analogue scale, SNOT-22 22-item sino-nasal outcome test, AR allergic rhinitis. The spearman correlation analysis method was used for analysis. P < 0.05 was considered significant. Bold text indicates that the difference is statistically significant and there is a correlation between the two indicators

ISSN: 1710-1492