Table 1 Results of investigations- respiratory Measurements
From: Autoinflammatory gene mutations associated with eosinophilia and asthma
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | |
|---|---|---|---|---|---|
FEV1(L) FEV1 (%) | 1.52 85 | 5.30 128 | 2.40 76 | 2.60 78 | 3.53 82 |
FVC (L) FVC (%) | 1.82 54 | 7.21 138 | 3.02 78 | 3.60 92 | 4.42 82 |
FEV1/FVC % | 84 | 73 | 79 | 65 | 77 |
Reversibility (%) | 9–12 | 3 | 3 | 22 | 12 |
PC20 methacholine (mg/ml) | Not done | 14 | 10.8 | 0.44 | 1 |
Skin prick test (# of + ve wheal and flare reactions) | 8 (HDM x 2, tree, grass, ragweed, Alternaria, cat, dog) | 1 (grass) | None | 1 (cat) | none |
Blood eosinophil count (109/L) (< 0.4 × 109/L)) | 0.67 | 0.9 | 5.8 | 0.7 | 1.2 |
FeNO (ppb) (< 25ppb) | 11 | 60 | 32 | 44 | 84 |
Sputum eosinophil (%) <2.2%) | 1.3 | 1.2 | 1.3 | 17.8 | 48.5 |
IgE (KIU/L) (< 87KIU/L) | 1240 | > 50,000 | 292 | 567 | 340 |
Tryptase (ug/L) (< 11.4 ug/L) | 4.7 | 2.6 | 10.2 | 3.8 | 2.2 |