Table 2 Case definition criteria and results

1*

1 of: 493

0.35

0.99

0.78

0.93

0.34

2

1 of: “asthma”

OR

1 of: 493 (asthma)

0.75

0.97

0.74

0.97

0.72

3*

1 of: “asthma”

OR

1 of: 493 (asthma)

0.04

1.00

0.60

0.91

0.04

4

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

0.81

0.96

0.70

0.98

0.77

5

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

Billing

Any of:

491 (chronic bronchitis),

492 (emphysema),

496 (COPD)

0.81

0.96

0.71

0.98

0.77

6

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

Encounter Diagnosis

Any of:

“asthma*query”

“query*asthma”

“asthma*?”

“?*asthma”

0.81

0.96

0.70

0.98

0.77

7

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

Billing

Any of:

491 (chronic bronchitis),

492 (emphysema),

496 (COPD)

AND/OR

Encounter Diagnosis

Any of:

“asthma*query”

“query*asthma”

“asthma*?”

“?*asthma”

0.81

0.96

0.71

0.98

0.77

8

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

0.81

0.96

0.70

0.98

0.77

9

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

Billing

Any of:

491 (chronic bronchitis),

492 (emphysema),

496 (COPD)

0.81

0.96

0.71

0.98

0.77

10

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

Encounter Diagnosis

Any of:

“asthma*query”

“query*asthma”

“asthma*?”

“?*asthma”

0.81

0.96

0.70

0.98

0.77

11

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

Billing

Any of:

491 (chronic bronchitis),

492 (emphysema),

496 (COPD)

AND/OR

Encounter Diagnosis

Any of:

“asthma*query”

“query*asthma”

“asthma*?”

“?*asthma”

0.81

0.96

0.71

0.98

0.77

12

2 of: 493

2 of: “asthma”

OR

2 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

0.78

0.97

0.75

0.98

0.75

13†

2 of: 493

2 of: “asthma”

OR

2 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

Encounter Diagnosis/Health Condition

“asthma*query”

“query*asthma”

“asthma*?”

“?*asthma”

0.78

0.97

0.75

0.98

0.75

14

1 of: 493

1 of: “asthma”

OR

1 of: 493 (asthma)

1 of: “asthma”

OR

1 of: 493 (asthma)

Any medication from asthma medication list

Medications

LAMA (monotherapy)

LABA

(monotherapy)

LAMA/LABA (monotherapy)

0.85

0.93

0.57

0.98

0.78

Medication

Case Definition

Inclusion Criteria (Any One Of)

Exclusion Criteria

SN

SP

PPV

NPV

YI

#1

#2

M-1

SABA

Budesonide/formoterol

Any other respiratory medication on medication list

0.35

0.96

0.47

0.93

0.31

M-2

SABA + ICS

SABA + LTRA

Any other respiratory medication on medication list

0.10

0.98

0.39

0.91

0.08

M-3

ICS

Any other respiratory medication on medication list

0.08

0.98

0.32

0.91

0.06

M-4

SABA + ICS/LABA

Any other respiratory medication on medication list

0.18

0.99

0.93

0.92

0.17

M-5

SABA + (ICS/LABA/LAMA OR ICS/LABA + LAMA OR ICS/LABA + LTRA OR ICS/LABA/LAMA + LTRA)

ICS/LABA/LAMA OR ICS/LABA + LAMA OR ICS/LABA + LTRA OR ICS/LABA/LAMA + LTRA

Any other respiratory medication on medication list

0.08

0.99

0.67

0.91

0.07

M-6

Biologics

Any other respiratory medication on medication list

0

0

0

0

-

M-7

Any medication from asthma medications list

LAMA (monotherapy)

LABA (monotherapy)

LAMA/LABA (monotherapy)

0.76

0.9

0.45

0.97

0.66