Fig. 2

Patient sample selection. Patients in the Merative MarketScan Commercial or Medicare Supplemental Databases with ≥ 2 non-ruleout (i.e., non-diagnostic) medical claims with a diagnosis of CRSwNP (as inferred by NP diagnosis codes; e.g., ICD-10-CM J33xx) in any position ≥ 1 day apart between 6/30/2018 and 6/30/2019. Reasons for biologic use were not available in the claims database; therefore, biologics may have been prescribed for conditions other than CRSwNP. *During identification period (6/30/2018–6/30/2019); ^†during the study period (6/30/2018–6/30/2020); ^‡during the observation period (7/1/2019–6/30/2020). CRSwNP, chronic rhinosinusitis with nasal polyps