IL-1β and iNOS can drive the asthmatic comorbidities and decrease of lung function in perennial allergic rhinitis children

Table 2 Univariate analysis to determine factors related to comorbidity of PAR and asthma (N = 240)

Variables	AR (N = 113)	Comorbidity (N = 127)	P-value
No paternal history of AR	91	90	0.056
Paternal history of AR	22	37	0.056
No Maternal history of AR	88	88	0.087
Maternal history of AR	25	39	0.087
IL-1β (≤ 10.84 pg/ml)	71	55	0.003
IL-1β (> 10.84 pg/ml)	42	72	0.003
CCL24 (≤ 308.0 pg/ml)	59	71	0.329
CCL24 (> 308.0 pg/ml)	54	56	0.329
iNOS (≤ 43.63 pg/ml)	61	3	0.038
iNOS (> 43.63 pg/ml)	52	74	0.038
E-cadherin (≤ 93.39 pg/ml)	61	57	0.101
E-cadherin (> 93.39 pg/ml)	52	70	0.101
Vimentin (≤ 486.0 pg/ml)	45	73	0.005
Vimentin (> 486.0 pg/ml)	68	54	0.005

PAR perennial allergic rhinitis, IL interleukin, CCL C–C motif chemokine ligand, iNOS inducible nitric oxide synthase

ISSN: 1710-1492