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Table 4 Expression of biomarkers (geometric mean and 95% CI) in the groups of normal lung function and decreased lung function (n = 239)

From: IL-1β and iNOS can drive the asthmatic comorbidities and decrease of lung function in perennial allergic rhinitis children

 

Normal PFT

(N = 126)

95% CI

Decreased PFT

(N = 113)

95% CI

p-value

Total IgE (IU/mL)

71.26

53.45-95.00

76.54

60.6-96.66

0.31

Eosinophils (%)

2.18

1.92–2.46

2.46

2.19–2.75

0.62

IL-1ß (pg/ml)

0.51

0.36–0.72

0.46

0.59–0.98

0.05

CCL24 (pg/ml)

198.22

167.20-234.58

240.23

197.54-292.16

0.15

iNOS(ng/ml)

15.54

10.78–22.37

38.39

29.55–49.87

< 0.001

E-cadherin(pg/ml)

101.80

95.94-108.09

106.8

87.96–108.00

0.36

Vimentin (pg/ml)

384.67

345.47-428.34

427.7

396.46-495.29

0.05

  1. PFT pulmonary function test, IL interleukin, CCL C–C motif chemokine ligand, iNOS inducible nitric oxide synthase CI confidence interval