From: The prevalence of obstructive sleep apnea in Japanese asthma patients
 | Without OSA (n = 17) | With OSA (n = 36) | P value |
---|---|---|---|
Male/Female, n (%) | 2/15 | 11/25 | 0.25 |
Age, years | 59.8 ± 16.8 | 58.7 ± 16.5 | 0.83 |
Age at asthma onset, years | 30.5 ± 22.8 | 58.7 ± 16.5 | 0.16 |
BMI, kg/m2 | 23.1 ± 3.85 | 27.9 ± 6.6 | < 0.01 |
Smoking status: Never/Ex./Current, n (%) | 13 (76.5)/2 (11.8)/2 (11.8) | 16 (44.5)/12 (33.3)/8 (22.2) | 0.29 |
Brinkman Index | 147.1 ± 398.6 | 290.5 ± 365.3 | 0.03 |
Hypertension, n (%) | 3 (17.6) | 16 (44.4) | 0.07 |
Diabetes, n (%) | 2 (11.8) | 12 (33.3) | 0.18 |
BNP, pg/ml | 28.6 ± 48.3 | 43.0 ± 82.9 | 0.17 |
GINA step (1/2/3/4/5), n (%) | 0/0/7 /7 /3 | 0/1/9/19/7 | 0.84 |
Allergic rhinitis, n (%) | 8 (47.1) | 17 (47.2) | 0.78 |
FSSG score | 6.82 ± 6.48 | 8.75 ± 9.94 | 0.76 |
ACT score | 22.4 ± 3.2 | 21.6 ± 3.7 | 0.31 |
ACQ-6 | 0.69 ± 0.83 | 1.09 ± 0.8 | 0.06 |
FeNO (ppb) | 37.7 ± 28.3 | 40.9 ± 43.2 | 0.71 |
Peripheral neutrophil count, cells/µL | 3603.5 ± 1468.4 | 4479.7 ± 2028.9 | 0.14 |
Peripheral eosinophil count, cells/µL | 582.1 ± 1311.6 | 280.2 ± 218.0 | 0.57 |
Serum IgE level, IU/mL | 583.6 ± 1359.5 | 603.84 ± 744.74 | 0.32 |
FVC, L | 2.77 ± 0.62 | 2.84 ± 0.67 | 0.65 |
FVC, % of predicted | 106.1 ± 15.7 | 96.7 ± 13.9 | 0.02 |
FEV1, L | 2.0 ± 0.7 | 1.99 ± 0.59 | 0.8 |
FEV1, % of predicted | 92.8 ± 19.1 | 82.4 ± 17.8 | 0.05 |
FEV1/FVC, % | 72.1 ± 12.8 | 70.1 ± 11.9 | 0.58 |
MMF, L | 1.5 ± 1.4 | 1.36 ± 0.87 | 0.92 |
MMF, % of predicted | 51.8 ± 39.6 | 45.1 ± 25.4 | 0.46 |
Epworth Sleepiness Scale | 6.35 ± 4.18 | 7.78 ± 4.83 | 0.27 |
Apnea Hypopnea Index | 5.0 ± 3.2 | 21.7 ± 16.0 | < 0.01 |
3% oxygen desaturation index | 5.2 ± 3.1 | 22.2 ± 18.4 | < 0.01 |
Lowest SpO2 | 86.9 ± 8.7 | 80.0 ± 8.5 | < 0.01 |