Table 2 Association analysis of mtSNP in AR group and control group
From: Two-stage association study of mitochondrial DNA variants in allergic rhinitis
SNP NO | Gene | Region | Rare Allele | FA | FC | OR (95%CI) | p-value | pBH | pB |
|---|---|---|---|---|---|---|---|---|---|
MT4715.A/G | ND2 | Synonymous | G | 4/132 | 24/108 | 0.1332(0.04467–0.3973) | 0.0003 | 0.0276 | 0.0276 |
MT15487.A/T | CYTB | Synonymous | T | 4/132 | 22/110 | 0.1494(0.04983–0.4477) | 0.000687 | 0.0316 | 0.0632 |
MT7196.C/A | COX1 | Synonymous | A | 4/132 | 22/110 | 0.1494(0.04983–0.4477) | 0.000687 | 0.0211 | 0.0632 |
MT302.-/CCC | NONE | Intergenic | CCC | 34/102 | 14/118 | 2.795(1.417–5.516) | 0.003037 | 0.0699 | 0.2794 |
MT6962.G/A | COX1 | Synonymous | A | 18/118 | 4/128 | 5.071(1.652–15.56) | 0.004547 | 0.0837 | 0.4183 |
MT10609.T/C | ND4L | Nonsynonymous | C | 16/120 | 4/128 | 4.5(1.442–14.04) | 0.009597 | 0.1472 | 0.8829 |
MT12406.G/A | ND5 | Nonsynonymous | A | 16/120 | 4/128 | 4.5(1.442–14.04) | 0.009597 | 0.1261 | 0.8829 |
MT12882.C/T | ND5 | Synonymous | T | 16/120 | 4/128 | 4.5(1.442–14.04) | 0.009597 | 0.1104 | 0.8829 |
MT16298.T/C | tRNA-Pro | Intergenic | C | 8/128 | 20/112 | 0.3442(0.1457–0.8133) | 0.01506 | 0.1111 | 1.0000 |
MT13759.G/A | ND5 | Nonsynonymous | A | 12/124 | 2/130 | 6.684(1.445–30.92) | 0.01507 | 0.1000 | 1.0000 |
MT16311.T/C | tRNA-Pro | Intergenic | C | 26/110 | 12/120 | 2.478(1.178–5.213) | 0.01682 | 0.0909 | 1.0000 |
MT8584.G/A | ATP6 | Nonsynonymous | A | 14/122 | 26/106 | 0.4546(0.225–0.9186) | 0.02805 | 0.0833 | 1.0000 |
MT14668.C/T | ND6 | Synonymous | T | 34/102 | 20/112 | 1.925(1.033–3.587) | 0.03914 | 0.0769 | 1.0000 |
MT8414.C/T | ATP8 | Nonsynonymous | T | 34/102 | 20/112 | 1.925(1.033–3.587) | 0.03914 | 0.0714 | 1.0000 |
MT16260.C/T | tRNA-Pro | Intergenic | T | 4/132 | 12/120 | 0.2953(0.09186–0.949) | 0.04058 | 0.0667 | 1.0000 |
MT10310.G/A | ND3 | Synonymous | A | 18/118 | 8/124 | 2.461(1.015–5.964) | 0.04618 | 0.0625 | 1.0000 |
MT6392.T/C | COX1 | Synonymous | C | 18/118 | 8/124 | 2.461(1.015–5.964) | 0.04618 | 0.0588 | 1.0000 |