Table 4 Allele distribution of mitochondrial SNP in validation cohort
From: Two-stage association study of mitochondrial DNA variants in allergic rhinitis
SNP NO | Gene | Genotype | Case | Control | χ2 | OR (95%CI) | p-value |
|---|---|---|---|---|---|---|---|
rs148377232 (MT16298.T/C) | tRNA-Pro | C | 8 | 10 | 1.722 | 0.512(0.186–1.408) | 0.190 |
T | 61 | 39 | |||||
rs1970771 (MT6962.G/A) | COX1 | A | 12 | 9 | 0.001 | 0.983(0.379–2.545) | 0.971 |
G | 57 | 42 | |||||
rs200487531 (MT10609.T/C) | ND4L | C | 12 | 9 | 0.007 | 0.959(0.370–2.487) | 0.932 |
T | 57 | 41 | |||||
rs28357370 (MT15487.A/T) | CYTB | T | 7 | 7 | 0.365 | 0.710(0.232–2.168) | 0.546 |
A | 62 | 44 | |||||
rs28357678 (MT14668.C/T) | ND6 | T | 12 | 5 | 1.464 | 1.971(0.647–6.005) | 0.226 |
C | 56 | 46 | |||||
rs28357976 (MT4715.A/G) | ND2 | G | 7 | 7 | 0.415 | 0.694(0.227–2.120) | 0.519 |
A | 62 | 43 | |||||
rs28358875 (MT7196.C/A) | COX1 | A | 7 | 7 | 0.365 | 0.710(0.232–2.168) | 0.546 |
C | 62 | 44 | |||||
rs28358884 (MT8414.C/T) | ATP8 | T | 12 | 5 | 1.388 | 1.937(0.636–5.896) | 0.239 |
C | 57 | 46 | |||||
G | 51 | 39 | |||||
rs28617389 (MT12406.G/A) | ND5 | A | 14 | 9 | 0.132 | 1.188(0.469–3.007) | 0.716 |
G | 55 | 42 | |||||
T | 48 | 32 | |||||
rs3135028 (MT8584.G/A) | ATP6 | A | 8 | 14 | 4.925 | 0.347(0.133–0.905) | 0.027 |
G | 61 | 37 | |||||
rs34799580 (MT16311.T/C) | tRNA-Pro | C | 10 | 7 | 0.030 | 1.084(0.382–3.073) | 0.880 |
T | 58 | 44 | |||||
G | 69 | 48 | |||||
rs373855397 (MT16260.C/T) | tRNA-Pro | T | 3 | 2 | 0.013 | 1.114(0.179–6.921) | 0.908 |
C | 66 | 49 | |||||
rs376513041 (MT6392.T/C) | COX1 | G | 15 | 12 | 0.036 | 0.920(0.388–2.183) | 0.850 |
T | 53 | 39 | |||||
C | 69 | 48 | |||||
A | 65 | 47 | |||||
rs386420001 (MT12882.C/T) | ND5 | T | 12 | 9 | 0.001 | 0.983(0.379–2.545) | 0.980 |
C | 57 | 42 | |||||
G | 63 | 46 | |||||
rs386420024 (MT13759.G/A) | ND5 | A | 11 | 7 | 0.136 | 1.213(0.435–3.384) | 0.712 |
G | 57 | 44 | |||||
A | 68 | 48 | |||||
rs41467651 (MT10310.G/A) | ND3 | T | 15 | 12 | 0.084 | 0.880(0.370–2.089) | 0.771 |
G | 54 | 38 |