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Fig. 7 | Allergy, Asthma & Clinical Immunology

Fig. 7

From: Circ_0070934 promotes MGAT3 expression and inhibits epithelial-mesenchymal transition in bronchial epithelial cells by sponging miR-199a-5p

Fig. 7

MGAT3 was a downstream target of miR-199a-5p. A There are potential base binding sites between MGAT3 and miR-199a-5p. B Dual-luciferase reporter assay was used to verify the binding relationship between MGAT3 and miR-199a-5p. C BEAS-2B cells were divided into four groups: vector, circ_0070934, si-NC and si-circ_0070934. D BEAS-2B cells were divided into four groups: miR-NC, miR-199a-5p mimics, inhibitor NC and miR-199a-5p inhibitor. C and D mRNA expression level of MGAT3 was determined by qRT-PCR. E and F The protein expression level of MGAT3 was determined by Western blot. The data were presented as mean ± SEM. Our experiments were repeated three times. ns, no significant; P > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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