Meeting abstracts
Allergy, Asthma & Clinical Immunology 2017 13(Suppl 2):29
Published on: 15 June 2017
This article is part of a Supplement: Volume 13 Supplement 2
Articles
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Short Report
Angioedema suppressed by a combination of anti-histamine and leukotriene modifier
Angioedema without co-existent urticaria is due to a limited number of causes, including hereditary and acquired C1 esterase inhibitor deficiency, drug-induced angioedema or idiopathic histaminergic or non-his...
Allergy, Asthma & Clinical Immunology 2017 13:28
Published on: 13 June 2017
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Research
A case series evaluating the serological response of adult asthma patients to the 23-valent pneumococcal polysaccharide vaccine
Asthma is an independent risk factor for invasive pneumococcal disease; however, the immune response of adult asthma patients to pneumococcal vaccination is unknown. We explore the serologic response of patien...
Allergy, Asthma & Clinical Immunology 2017 13:27
Published on: 7 June 2017
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Research
Maternal sensitivity and social support protect against childhood atopic dermatitis
Many studies have identified associations between qualities of maternal–child relationships and childhood asthma, but few have examined associations with childhood atopic dermatitis (AD), a common precursor to...
Allergy, Asthma & Clinical Immunology 2017 13:26
Published on: 26 May 2017
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Research
The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria
Up-regulation of interleukin 17 (IL-17) family cytokines and acute phase response have been observed in patients with chronic spontaneous urticaria (CSU). It has been demonstrated that IL-17 stimulates C-react...
Allergy, Asthma & Clinical Immunology 2017 13:25
Published on: 10 May 2017
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Research
Visual analogue scale (VAS) as a monitoring tool for daily changes in asthma symptoms in adolescents: a prospective study
Success in asthma management hinges on patients’ competency to detect and respond to ever-changing symptom severity. Thus, it is crucial to have reliable, simple, and sustainable methods of symptom monitoring ...
Allergy, Asthma & Clinical Immunology 2017 13:24
Published on: 28 April 2017
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Case Report
Systemic mastocytosis with KIT V560G mutation presenting as recurrent episodes of vascular collapse: response to disodium cromoglycate and disease outcome
Mastocytosis are rare diseases characterized by an accumulation of clonal mast cells (MCs) in one or multiple organs or tissues. Patients with systemic mastocytosis (SM), whose MCs frequently arbor the activat...
Allergy, Asthma & Clinical Immunology 2017 13:21
Published on: 24 April 2017
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Research
Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor
Interleukin-31 (IL-31) is a recently identified cytokine produced by Th2 cells that is involved in the development of atopic dermatitis-induced skin inflammation and pruritus. Its receptor, IL-31RA, is express...
Allergy, Asthma & Clinical Immunology 2017 13:23
Published on: 17 April 2017
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Research
Preconception allergen sensitization can induce B10 cells in offspring: a potential main role for maternal IgG
The mechanisms through which allergies can be inhibited after preconception immunization with allergens are not fully understood. We aimed to evaluate whether maternal immunization can induce a regulatory B (B...
Allergy, Asthma & Clinical Immunology 2017 13:22
Published on: 17 April 2017
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Meeting abstracts
Allergy, Asthma & Clinical Immunology 2017 13(Suppl 1):16
Published on: 7 April 2017
This article is part of a Supplement: Volume 13 Supplement 1
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Research
Nasal nitric oxide in allergic rhinitis in children and its relationship to severity and treatment
Nasal nitrous oxide (nNO) is increased in allergic rhinitis (AR), but not in asthma, and is a non-invasive marker for inflammation in the nasal passages.
Allergy, Asthma & Clinical Immunology 2017 13:20
Published on: 4 April 2017
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Research
Sputum cell counts to manage prednisone-dependent asthma: effects on FEV1 and eosinophilic exacerbations
Prednisone dependence in asthma is usually described based on clinical and spirometric characteristics. It is generally believed that these patients have frequent exacerbations and lose lung function rapidly b...
Allergy, Asthma & Clinical Immunology 2017 13:17
Published on: 4 April 2017
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Research
Consumer preferences for food allergen labeling
Food allergen labeling is an important tool to reduce risk of exposure and prevent anaphylaxis for individuals with food allergies. Health Canada released a Canadian food allergen labeling regulation (2008) an...
Allergy, Asthma & Clinical Immunology 2017 13:19
Published on: 4 April 2017
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Research
Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies
Antagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein coupled receptor for prostaglandin D2, could be beneficial for treating allergic disorders. We present f...
Allergy, Asthma & Clinical Immunology 2017 13:18
Published on: 4 April 2017
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Research
Elevated expression of TIGIT on CD3+CD4+ T cells correlates with disease activity in systemic lupus erythematosus
It is well-known that lymphocytes play an important role in systemic lupus erythematosus (SLE). T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory domains (TIGIT) is one of immunosuppre...
Allergy, Asthma & Clinical Immunology 2017 13:15
Published on: 28 February 2017
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Review
Gene therapy for primary immune deficiencies: a Canadian perspective
The use of gene therapy (GT) for the treatment of primary immune deficiencies (PID) including severe combined immune deficiency (SCID) has progressed significantly in the recent years. In particular, long-term...
Allergy, Asthma & Clinical Immunology 2017 13:14
Published on: 27 February 2017
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Research
Dietary intake is associated with respiratory health outcomes and DNA methylation in children with asthma
Asthma is an increasingly common chronic disease among children, and data point toward a complex mechanism involving genetic, environmental and epigenetic factors. Epigenetic modifications such as DNA hypo- or...
Allergy, Asthma & Clinical Immunology 2017 13:12
Published on: 27 February 2017
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Case Report
An avoidable cause of thymoglobulin anaphylaxis
Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injectio...
Allergy, Asthma & Clinical Immunology 2017 13:13
Published on: 23 February 2017
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Letter to the editor
Allergic rhinitis: the eligible candidate to mite immunotherapy in the real world
As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House d...
Allergy, Asthma & Clinical Immunology 2017 13:11
Published on: 21 February 2017
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Letter to the editor
Primum non nocere—first do no harm. And then feed peanut
The Addendum Guidelines for the Prevention of Peanut Allergy in the United States—Report of the NIAID-Sponsored Expert Panel were developed to build on previous food allergy guidelines after several key studies d...
Allergy, Asthma & Clinical Immunology 2017 13:7
Published on: 8 February 2017
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Research
Prevalence of allergen sensitization in 1000 adults in Saskatchewan
The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More impo...
Allergy, Asthma & Clinical Immunology 2017 13:9
Published on: 8 February 2017
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Research
Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma
We aimed to determine the effect of sampling time during the day on serum periostin levels in adult participants with and without asthma.
Allergy, Asthma & Clinical Immunology 2017 13:8
Published on: 8 February 2017
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Research
Prediction of clinical peanut allergy status among children in Hamilton, Ontario using chart review data collected during 2012–2015
Peanut sensitization does not necessarily indicate clinical peanut allergy, and uncertainty as to whether or not there is true peanut allergy can lead to increased anxiety and decreased quality of life for pat...
Allergy, Asthma & Clinical Immunology 2017 13:10
Published on: 8 February 2017
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Case report
Atopic keratoconjunctivitis complicated by Kocuria koreensis keratitis: the first case
Patients with atopic dermatitis have a predisposition to Staphylococcus aureus and a Herpes simplex virus infection. The treatment of atopic diseases with steroid and immunosuppressive agents induces opportunisti...
Allergy, Asthma & Clinical Immunology 2017 13:6
Published on: 25 January 2017
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Short report
Hereditary angioedema: health-related quality of life in Canadian patients as measured by the SF-36
Hereditary angioedema (HAE) is a rare but serious condition characterized by recurrent spontaneous attacks of angioedema affecting superficial tissues of upper respiratory and gastrointestinal tracts. The pote...
Allergy, Asthma & Clinical Immunology 2017 13:4
Published on: 19 January 2017
