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  1. Hereditary angioedema (HAE) is characterized by debilitating attacks of tissue swelling in various locations. While guidelines recommend the importance of early on-demand treatment, recent data indicate that m...

    Authors: Stephen D. Betschel, Teresa Caballero, Douglas H. Jones, Hilary J. Longhurst, Michael Manning, Sally van Kooten, Markus Heckmann, Sherry Danese, Ledia Goga and Autumn Ford Burnette
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:43
  2. Glucocorticoids are widely used in inhalation aerosol therapy for wheezing diseases. This study aims to explore guardians’ knowledge and attitude towards inhaled corticosteroids (ICS) aerosol therapy and the m...

    Authors: Zuojiao Liu, Haiqing Dai, Fengjiao Tao, Xiaoxiao He and Ting Jin
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:42
  3. Associations between psoriasis and allergic diseases (asthma, rhinitis, and eczema) in children have been reported in a limited number of studies, and the association between psoriasis and multimorbidity (co-o...

    Authors: Ali H. Ziyab, Yaser Ali, Dina Zein, Manal Al-Kandari, John W. Holloway and Wilfried Karmaus
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:41
  4. To explore the role of different cells and molecules in the pathogenesis of allergic rhinitis (AR) with positive Artemisia allergen by detecting their expression levels.

    Authors: Li-Ping Guo, Min Yan, Rui-Bing Niu, Lei Liu, Jing-Ru Yang, Rui-Lian Chen, Bao-Sheng Duan, Cui-Cui Li and Jian-Xiong Li
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:40
  5. Azathioprine is a purine synthesis inhibitor used as an immunosuppressive therapy for many immune-mediated diseases. Azathioprine hypersensitivity reaction is a rare, life-threatening adverse reaction characte...

    Authors: Samuel Su, Yu Ming Wang, Karver Zaborniak, Sate Hamza, Davinder S. Jassal and Marcus Blouw
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:39
  6. Despite asthma guidelines’ recommended emergency department preventative strategies (EDPS), repeat asthma-related emergency department (ED) visits remain frequent.

    Authors: Tahereh Haji, Lynnette Lyzwinski, Cara Dhaliwal, Garvin Leung, Sandra Giangioppo and Dhenuka Radhakrishnan
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:37
  7. Recombinant human Interleukin receptor antagonist (rhIL-Ra) can bind to the IL-1 receptor on the cell membrane and reversibly blocks the proinflammatory signaling pathway. However, its effect on allergic rhini...

    Authors: Haibing Li, Chanjuan Di, Yanbing Xie, Yuexia Bai and Yongxue Liu
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:36
  8. Anaphylaxis is the most severe form of acute systemic and potentially life-threatening reactions triggered by mast and basophilic cells. Recent studies show a worldwide incidence between 50 and 112 occurrences...

    Authors: Simone Ehrhard, Vicky Eyb, Dominic Gautschi, Stefan K. Schauber, Meret E. Ricklin, Jolanta Klukowska-Rötzler, Aristomenis K. Exadaktylos and Arthur Helbling
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:35
  9. Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease characterized by inflammation of the nasal and sinus mucosa. The inflammatory patterns may differ among patients, leading to differe...

    Authors: Yu-Tsai Lin, Ming-Hsien Tsai, Yan-Ye Su and Shun-Chen Huang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:34
  10. Diet restrictions and fear of adverse reactions put a significant burden on the nutrition, growth and life style of children and adults with food allergies. While various disease-modifying options are pursued,...

    Authors: Lydia M. Theodoropoulou and Niamh A. Cullen
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:33
  11. Since the last guidance was published by the Canadian Thoracic Society, there have been several advances in the clinical management of severe asthma. To gain a better understanding of the current standards of ...

    Authors: Krystelle Godbout, Harold Kim, Irvin Mayers, James Paterson and Charles K. N. Chan
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:31
  12. Immunoglobulin replacement therapy is a standard treatment for patients with antibody production deficiencies, which is of interest in patients with chronic obstructive pulmonary disease (COPD). This systemati...

    Authors: Justin J. Y. Kim, Liz Dennett, Maria B. Ospina, Anne Hicks, Harissios Vliagoftis and Adil Adatia
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:30
  13. Serum-sickness like reactions (SSLRs) to amoxicillin have been documented in the medical literature. Beta-lactams are important and commonly used medications especially in the pediatric population. Often, SSLR...

    Authors: Devyani Bakshi, Xinxin Tang and Susan Waserman
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:29
  14. Hereditary angioedema (HAE) poses diagnostic challenges due to its episodic, non-specific symptoms and overlapping conditions. This study focuses on the genetic basis of HAE, particularly focusing on unresolve...

    Authors: Marija Rozevska, Adine Kanepa, Signe Purina, Linda Gailite, Inga Nartisa, Henriette Farkas, Dmitrijs Rots and Natalja Kurjane
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:28
  15. A significant update was made to both the Global Initiative for Asthma (GINA) in 2019 and the National Heart Lung and Blood Institute (NHLBI) asthma guidelines in 2020 for mild asthma. These groups no longer r...

    Authors: Beth A. Zerr, Jacklyn M. Kruse and Jon J. Glover
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:27
  16. Hereditary alpha-tryptasemia (HαT) is an autosomal dominant disorder estimated to affect 5% of the population. High baseline tryptase level is a consistent finding, but there is a great variability of clinic m...

    Authors: Vicky Le Blanc and Wade T. A. Watson
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:26
  17. Systemic corticosteroid (SCS) use remains widespread among patients with severe asthma, despite associated complications.

    Authors: Thomas B Casale, Thomas Corbridge, Guillaume Germain, François Laliberté, Sean D MacKnight, Julien Boudreau, Mei S Duh and Arijita Deb
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:25
  18. Asthma exacerbations are a leading cause of pediatric hospitalizations despite multiple efforts to educate patients and families on disease course and medication management. Asthma education in the pediatric e...

    Authors: Kina Goodman, Rosa I. Arriaga, Rawan Korman, Farzina Zafar, Cal Stephens, Polly Kumari, Karthika Jayaprakash, Anne M. Fitzpatrick, Nicholas Cooper and Claudia R. Morris
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:24
  19. Circular RNA (circRNA) has the potential to serve as a crucial regulator in the progression of bronchial asthma. The objective of this investigation was to elucidate the functional dynamics of the circ_0070934...

    Authors: Ziqi Ding, Xinru Xiao, Liang Fan, Zhengdao Mao, Chuang Sun, Na Li and Qian Zhang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:23
  20. The poly-sensitization to Hymenoptera venom makes it difficult to select genuine allergens for immunotherapy and increases patients’ costs. The objective of this study was to determine the culprit allergen in ...

    Authors: Mohammad Hassan Bemanian, Raheleh Shokouhi Shoormasti, Saba Arshi, Mahsa Jafari, Sima Shokri, Morteza Fallahpour, Mohammad Nabavi and Fatemeh Zaremehrjardi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:22
  21. While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity.

    Authors: Zoe Harbottle, Amanda Nötzel, Michael A. Golding, Manvir Bhamra, Isac Kopsch, Erik Wilking, Marina Jonsson, Elissa M. Abrams, Michelle A. Halbrich, Elinor Simons, Leslie E. Roos, Jill A. Keddy-Grant, Thomas V. Gerstner, Jo-Anne St-Vincent, Sandra Ekström and Jennifer L. P. Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:21
  22. Self-reported penicillin allergy labels are common and often inaccurate after assessment. These labels can lead to reduced use of first-line beta-lactam antibiotics and worse outcomes. We measured the impact o...

    Authors: Adhora Mir, Derek Lanoue, Veronica Zanichelli, Carl van Walraven, Timothy Olynych, Caroline Nott and Derek MacFadden
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:20
  23. Eosinophilic gastritis (EoG) has rarely been reported in conjunction with gluten-sensitive enteropathy (GSE). When this does occur, patients typically present with gastrointestinal symptoms. To our knowledge, ...

    Authors: Zhirong Du, Zixi Wang, Weixun Zhou, Jia Yin and Yuxiang Zhi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:19
  24. In this letter to the editor, we present questionnaire-based data assessing the patient journey of adults with moderate–severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in the USA and five European cou...

    Authors: Jeremiah Hwee, Lauren Lee, Mark Small, Steven G. Smith, Victoria S. Benson and Shiyuan Zhang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:17
  25. Correlations between mitochondrial DNA (mtDNA) and allergic rhinitis (AR) have not been reported before. This study aimed to better understand the mitochondrial genome profile with AR and to investigate the as...

    Authors: Huajie Yuan, Lingling Wang, Song Wang, Linge Li, Qingping Liu, Yan Wang, Yuping Yang and Hua Zhang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:16
  26. While a connection has been established between serum interleukin-6 (IL-6) levels and the IL-6 gene (− 174G/C) polymorphism in allergic diseases such as asthma, its specific association with severe asthma remains...

    Authors: Mona Al-Ahmad, Asmaa Ali, Ahmed Maher and Mohammad Z. Haider
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:15
  27. Chronic Rhinosinusitis (CRS) is a paranasal sinus inflammatory disease and is divided into two subgroups defined as CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). CRSwNP displays a T hel...

    Authors: Javad Nazari, Faezeh Shahba, Negin Jafariaghdam, Saleh Mohebbi, Saba Arshi, Mohammad Hassan Bemanian, Morteza Fallahpour, Sima Shokri, Fatemeh Atashrazm, Saeed Amini, Maryam Roomiani, Mahnaz Jamee, Pegah Babaheidarian, Majid Khoshmirsafa and Mohammad Nabavi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:14
  28. According to the Th1/Th2 paradigm, the expansion of Th1-type clones in individuals with type 1 diabetes results in reduced Th2-type clones, preventing the development of atopic diseases and vice versa. However...

    Authors: Júlia Marchatto Kamei, Raissa Dias Maués, Gabriel de Oliveira Silva, Alessandra Helena Machado, Erika Megumi Hoshino, Fabiana Menezes Bacchiega, Laís Mota Furtado Sena and Carlos Antonio Negrato
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:12
  29. Mepolizumab, the first widely available anti-interleukin 5 biologic, targets eosinophilic inflammation and has been shown in clinical trials to reduce exacerbations, oral corticosteroid dependence, and healthc...

    Authors: Kenneth R. Chapman, Kathryn Cogger, Erin Arthurs, Callahan LaForty, Shane Golden, Bradley Millson, Koyo Usuba and Christopher Licskai
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:11
  30. Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the general population because these conditions share some comorbidities. In Japan, the prevalence of OSA in the general population...

    Authors: Mina Yasuda, Kazunori Tobino, Norihiro Harada, Ryunosuke Ooi, Takuto Sueyasu, Saori Nishizawa, Miyuki Munechika, Kohei Yoshimine, Yuki Ko, Yuki Yoshimatsu, Kosuke Tsuruno, Hiromi Ide and Kazuhisa Takahashi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:10
  31. Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE) -mediated food allergy predominantly observed in infants and characterized by the delayed onset of vomiting following ingesti...

    Authors: Hunter Hall, Sara Anvari, Fallon Schultz, Olubukola Ojuola and Nicholas L. Rider
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:9
  32. Proteinase-activated receptor 2 (PAR-2) is a G-protein coupled receptor associated with many inflammatory diseases, including asthma. We have shown an association between PAR-2 expression in peripheral blood m...

    Authors: Nami Shrestha Palikhe, Qahir Haji, Emily Mack, Tristan Sinnatamby, Andrew J. Sandford, Lisa Cameron and Harissios Vliagoftis
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:8
  33. Inborn errors of immunity (IEIs) are a group of conditions whereby parts of the immune system are missing or dysfunctional. Once thought to primarily be a pediatric disorder, it is now estimated that more than...

    Authors: Joanne J. F. Wang, Arün Dhir, Kyla J. Hildebrand, Stuart E. Turvey, Robert Schellenberg, Luke Y. C. Chen, Persia Pourshahnazari and Catherine M. Biggs
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:6
  34. Poor sleep health is associated with increased asthma morbidity and mortality. Accelerometers have been validated to assess sleep parameters though studies using this method in patients with asthma are sparse ...

    Authors: Varun Sharma, Helen Clare Ricketts, Femke Steffensen, Anna Goodfellow, Duncan S Buchan and Douglas C Cowan
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:5
  35. H. pylori is a gram-negative bacterium that is usually acquired in childhood and can persistently colonize the gastric mucosa of humans, affecting approximately half of the world’s population. In recent years,...

    Authors: Mengmeng Liu, Yong Wang and Bing Du
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:4
  36. Interleukin (IL)-36 family is closely associated with inflammation and consists of IL-36α, IL-36β, IL-36γ, and IL-36Ra. The role of IL-36 in the context of asthma and asthmatic phenotypes is not well character...

    Authors: Jinyan Li, Zhengda Wang, Hongna Dong, Yuqiu Hao, Peng Gao and Wei Li
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:3
  37. Allergic asthma and rhinitis (AR) are closely linked, with a significant proportion of AR patients developing asthma. Identification of the early signs of comorbidity of AR and asthma can enable prompt treatme...

    Authors: Myung Woul Han, Song Hee Kim, Inbo Oh, Yang ho Kim and Jiho Lee
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:1
  38. Increasing evidence suggests that hormone therapy (HT) and obesity exert an influence on allergic rhinitis (AR). It is important to investigate the association and interactions between HT, BMI, and AR in perim...

    Authors: Jingyi Liu, Tingting Ma, Xiaoxue Wang, Wenpei Bai and Xueyan Wang
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:107
  39. Real-world data on subcutaneous C1INH (C1INH[SC]) usage and patient-level impacts on hereditary angioedema (HAE)-related outcomes and quality of life (QoL) are both lacking and challenging to generate using co...

    Authors: William Lumry, Timothy Craig, John Anderson, Marc Riedl, Henry Li, Raffi Tachdjian, Michael Manning, Paolo Bajcic, Frank Rodino, Sam Wang, Thomas R. Sexton and Jonathan A. Bernstein
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:105
  40. Several biologics are now approved in the US as add-on treatments for chronic rhinosinusitus with nasal polyps (CRSwNP). This cross-sectional, retrospective, real-world study aimed to characterize treatment pa...

    Authors: Jared Silver, Elizabeth Packnett, Julie Park and Arijita Deb
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:104
  41. Non-esophageal eosinophilic gastrointestinal disorder (non-EoE-EGID) is a rare disease in which eosinophils infiltrate parts of the gastrointestinal tract other than the esophagus; however, the number of patie...

    Authors: Mitsuru Tsuge, Kenji Shigehara, Kazuhiro Uda, Seiji Kawano, Masaya Iwamuro, Yukie Saito, Masato Yashiro, Masanori Ikeda and Hirokazu Tsukahara
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:103
  42. The diagnosis of Alpha-gal Syndrome (AGS) is based on the presence of symptoms after being exposed to potential sources of alpha-gal together with values ​​of specific IgE (sIgE) to alpha-gal ≥ 0.1 kUA/L or ≥ ...

    Authors: Adrián Germán-Sánchez, Ana Alonso-Llamazares, Fernando García-González, Bakai Matala-Ahmed, Ceny Solani Melgar-Reyes and Ignacio Antepara-Ercoreca
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:102

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