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Table 2 Differences in baseline characteristics between the subjects who obtained clinical tolerance and those who failed

From: Home-based oral immunotherapy (OIT) with an intermittent loading protocol in children unlikely to outgrow egg allergy

Characteristic

Group

P value

 

Tolerance (N = 11)

Failure (N = 19)

 

Age at challenge test

   

 Median

6.00

6.00

0.081

 Range

6.00 - 12.00

5.00 - 11.00

 

Initial total IgE antibody level - UA/ml

   

 Median

668.0

997.0

0.378

 Range

108.5 - 3801.0

161.5 - 9978.0

 

Initial egg-specific IgE antibody level - UA/ml

   

 Median

14.60

25.50

0.012

 Range

5.25 - 27.80

5.33 - 100.00

 

Duration since Last Episode - yr

   

 Median

2.00

2.00

0.758

 Range

0.50 - 6.00

0.00 - 6.00

 

Condition of elimination*

   

 Partial

9.1

5.3

1.000

 Complete

90.9

94.7

 

Having other food allergies*

   

 No

18.2

10.5

0.611

 Yes

81.8

89.5

 

Frequency of allergic symptoms at accidental ingestion*

   

 Never

27.3

15.8

0.807

 Once

9.1

15.8

 

 2-10 times

54.5

63.2

 

 >10 times

9.1

5.3

 

Grade of anaphylaxis at accidental ingestion*

   

 1

90.9

63.2

0.095

 2

9.1

26.3

 

 3

0.0

0.0

 

 4

0.0

10.5

 

Frequency of emergency visit at accidental ingestion*

   

 Never

100

73.7

0.068

 Once

0.0

15.8

 

 2-5 times

0.0

10.5

 

Grade of anaphylaxis at challenge test*

   

 1

72.7

31.6

0.020

 2

18.2

21.1

 

 3

9.1

47.4

 

 4

0.0

0.0

 

Symptoms during challenge test*

   

 Respiratory: cough, asthma, difficulty in breathing

9.1

52.6

0.023

 Skin: rash, hives, eczema

54.5

63.2

0.712

 Gastrointestinal: vomiting, diarrhea, abdominal pain

27.3

26.3

1.000

Dislike of Eggs*

   

 No

90.9

89.5

1.000

 Yes

9.1

10.5

 
  1. *percentage within the group.