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Table 3 Adverse events and treatments during oral immunotherapy (OIT)

From: Home-based oral immunotherapy (OIT) with an intermittent loading protocol in children unlikely to outgrow egg allergy

Situation

 

Symptom type

Total frequency

Oral

GI

Skin

Resp.

Other

 

times per trial per person * × 100(%)

At home

0.485

0.091

0.262

0.100

0.079

0.081

With dose build-up

9.117

1.150

3.450

3.583

1.283

2.350

Situation

Treatment

Oral anti-histamine

Oral betamethasone

Topical steroid

Nebulized β 2 stimulant

Intravenous prednisone

 

times per trial per person * × 100(%)

At home

0.360

0.058

0.010

0.015

0.005

With dose build-up

4.183

0.000

2.433

0.983

0.000

  1. *The number of adverse reactions was divided by the number of trials of each patient, and then an average value for the 30 patients was calculated.
  2. The OIT duration of all patients was 0.50 - 5.25 years (median, 2.54 years); trials at home, 65 - 685 times (median, 331 times); trials with dose build-up, 3 - 32 times (median, 15 times).
  3. GI, gastrointestinal: abdominal pain, vomiting, diarrhea.
  4. Resp., respiratory: cough, wheeze, asthma, difficulty in breathing.
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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