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Table 2 Medications approved for the treatment of acute HAE attacks

From: The prophylactic use of C1 inhibitor in hereditary angioedema patients undergoing invasive surgical procedures: a retrospective study

Treatment of acute attacks

Medication class

Example

Dose

Approval

Canada

US

Europe

C1 INH Replacement (plasma derived)

Berinert

20 U/kg IV

✓

✓

✓

Cetor

1000 U IV

  

✓

Cinryze

1000 U IV

  

✓

Recombinant C1 INH

Ruconest

50 U/kg IV

  

✓

Rhucin

50 U/kg IV

 

Pending

 

Kallikrein Inhibitor

Ecallantide

30 mg SC

 

✓

 

Bradykinin antagonist

Icatibant

30 mg SC

Pending

✓

✓