Treatment of acute attacks | |||||
---|---|---|---|---|---|
Medication class | Example | Dose | Approval | ||
Canada | US | Europe | |||
C1 INH Replacement (plasma derived) | Berinert | 20 U/kg IV | ✓ | ✓ | ✓ |
Cetor | 1000 U IV | ✓ | |||
Cinryze | 1000 U IV | ✓ | |||
Recombinant C1 INH | Ruconest | 50 U/kg IV | ✓ | ||
Rhucin | 50 U/kg IV | Pending | |||
Kallikrein Inhibitor | Ecallantide | 30 mg SC | ✓ | ||
Bradykinin antagonist | Icatibant | 30 mg SC | Pending | ✓ | ✓ |