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Table 3 Characteristics of patients with NSAID hypersensitivity and basal serum tryptase level > 20 ng/mL

From: Non-steroidal anti-inflammatory drug hypersensitivity: association with elevated basal serum tryptase?

Patient

Age, sex

Drug

Application

Latency [minutes]

Anaphylaxis [grade]

Treatment

Tryptase [ng/mL]

Classification of Mastocytosis

#1

54, f

Acetylsalicylic acid

Oral

15

1

H1-blocker

39.7

ISM

#2

61, f

Acetylsalicylic acid

Oral

30

1

No

42.2

ISM

#3

72, f

Metamizol

Oral

20

1

No

23.5

CM

#4

54, f

Diclofenac

Oral

20

1

No

32.7

n.d.

#5

37, f

Acetylsalicylic acid

Oral

30

2

H1-blocker, steroids

26.2

n.d.

#6

71, f

Diclofenac

Oral

10

2

H1-blocker

94.8

ISM

  1. ISM, indolent systemic mastocytosis. CM, cutaneous mastocytosis. n.d., not determined yet.