Table 1 Summary of effects of LTRA in all studies
From: Leukotriene receptor antagonists for chronic urticaria: a systematic review
Outcome measure | Studies | LTRA vs Placebo | LTRA + AH vs AH | LTRA vs AH |
|---|---|---|---|---|
Pruritus | Di Lorenzo et al. | ND | ND | Favours AH |
Reimers et al. | ND | - | - | |
Kosnik et al. | - | ND | - | |
Nettis et al. [14] | - | Favours LTRA | - | |
Godse | - | - | Favours AH | |
Number of weals | Di Lorenzo et al. | Favours LTRA | ND | Favours AH |
Reimers et al. | ND | - | - | |
Kosnik et al. | - | ND | - | |
Nettis et al. [14] | - | Favours LTRA | - | |
Interference with sleep | Di Lorenzo et al. | ND | ND | Favours AH |
Reimers et al. | ND | - | - | |
Kosnik et al. | - | ND | - | |
Interference with daily activities | Di Lorenzo et al. | Favours LTRA | ND | ND |
Reimers et al. | ND | - | - | |
Quality of life score | Agcaoili et al. | ND | - | - |
Nettis et al. [14] | - | Favours LTRA | - | |
TSS | Di Lorenzo et al. | Favours LTRA | ND | Favours AH |
Nettis et al. [23] | - | - | Favours LTRA | |
Size of weals | Di Lorenzo et al. | ND | ND | - |
UAS | Erbagci et al. | Favours LTRA | - | - |
Agcaoili et al. | Favours LTRA | - | - | |
Kosnik et al. | - | ND | - | |
Wan et al. | - | ND | - | |
Godse | - | - | Favours AH | |
Weekly AH count | Erbagci et al. | Favours LTRA | - | - |
Visual analog scale | Bagenstose et al. | - | Favours LTRA | - |
Nettis et al. | - | Favours LTRA | - | |
Wan et al. | - | ND | - | |
TES | Bagenstose et al. | - | ND | - |