Table 1 Baseline demographics and clinical characteristics of pediatric subjects in the mOIT, rush mOIT, and control groups
mOIT* | Rush mOIT* | Control | |
|---|---|---|---|
Number of subjects | 29 | 11 | 10 |
Median age in years (range) | 8 (4 – 13) | 7 (4 – 16) | 8 (4–14) |
Male | 18 (62%) | 8 (72%) | 5 (50%) |
Coexisting atopic disease | |||
Atopic dermatitis | 20 (69%) | 5 (45%) | 5 (50%) |
Allergic rhinitis | 15 (52%) | 6 (55%) | 6 (60%) |
Asthma | 21 (72%) | 8 (73%) | 7 (70%) |
Food allergies meeting criteria for inclusion on DBPCFC** | |||
Peanut | 20 (69%) | 7 (64%) | 7 (70%) |
Walnut | 11 (38%) | 5 (45%) | 4 (40%) |
Cashew | 9 (31%) | 6 (55%) | 3 (30%) |
Pecan | 8 (28%) | 5 (45%) | 3 (30%) |
Milk | 8 (28%) | 3 (27%) | 2 (20%) |
Egg | 4 (14%) | 4 (36%) | 3 (30%) |
Sesame | 4 (14%) | 0 (0%) | 2 (20%) |
Almond | 3 (10%) | 3 (27%) | 2 (20%) |
Hazelnut | 2 (7%) | 1 (9%) | 2 (20%) |
Average number of desensitized foods | |||
3 | 4 | n/a | |
Highest baseline food allergy test (median and range) | |||
SPT in mm | 13.5 (7–25.5) | 10.5 (7–29.5) | 10.5 (7–30.5) |
Specific IgE in ku/L | 82.5 (2.95- > 100) | 36.4 (2- > 100) | 61 (3.25- > 100) |
Lowest amount triggering reaction in DBPCFC in mg protein | 32.7 (0.1-182.7) | 32.7 (0.1-182.7) | 32.7 (0.1-182.7) |