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Table 3 Mixed model ANCOVA of mean congestion and TNSS scores (2–6 hours)

From: Add-on histamine receptor-3 antagonist for allergic rhinitis: a double blind randomized crossover trial using the environmental exposure unit

 

Difference (test – reference)

Sequences 5–8: congestion

 
 

N

Adjusted mean

SE

Adjusted mean

SE

90% CI

Prob

<-0.15

PF-03654764

86

1.58

0.106

0.07

0.080

(-0.06, 0.20)

0.0035

+ fexofenadine

Pseudoephedrine

87

1.51

0.107

    

+ fexofenadine

Sequences 5–8: TNSS

    
 

N

Adjusted Mean

SE

Adjusted Mean

SE

90% CI

Prob NI

PF-03654764

86

3.81

0.288

-0.08

0.233

(-0.46, 0.31)

1.000

+ fexofenadine

Pseudoephedrine

87

3.89

0.289

    

+ fexofenadine

  1. The primary analysis consisted of a mixed effects ANCOVA with period and treatment fixed effects and subject random effect, employing sequences 5–8 to compare PF-03654764.
  2. + fexofenadine to pseudoephedrine + fexofenadine. N = number of non-missing observations included in the analysis.
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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