Table 1 Characteristics of iGAS patients and streptococcal strains
Patient number | Age at iGASd (years) | Delay between assay and iGASd (years) | iGASd manifestations | emm-type | Virulence factors gene profile |
|---|---|---|---|---|---|
1 | 1.6 | 0.5 | Necrotizing fasciitis/osteomyelitis | 12 | spe A, spe B, spe C, ssa |
2 | 3.1 | 1.6 | pneumonia with empyema | 1 | spe A, spe B, sme Z-1, sic |
3 | 5.1 | 1.4 | bacteremia | 1 | spe A, spe B, sme Z-1, sic |
4 | 6.2 | 1.4 | Cellulites with bacteremia | 1 | spe A, spe B, sme Z-1, sic |
5 | 10.3 | 0.1 | osteomyelitis | 12 | spe B, spe C, ssa |
6 | 7.0 | 0.1 | bacteremia | 12 | spe B, spe C, ssa |
7 | 3.4 | 0.2 | pneumonia with empyema | 1 | spe B, ssa, sme Z-1, sic |
8 | 16.2 | 3.4 | necrotizing fasciitis | 5 | spe B. spe C |
9 | 9.4 | 3.2 | necrotizing fasciitis | 4 | spe B, spe C, ssa, sme Z-1 |
10 | 8.8 | 0.2 | bacteremia | 1 | spe B, ssa, sme Z-1 |
11 | 1.8 | 1.7 | bacteremia | 4 | spe B, spe C, ssa, sme Z-1 |
12 | 3.8 | 0.2 | pneumonia with empyema | nd | nd |
13 | 4.6 | 4.5 | meningitis | 89 | spe B, spe C |
14 | 1.9 | 4.0 | bacteremia | 49 | spe B |
15 | 6.1 | 3.9 | arthritis | 4 | spe C, ssa, sme Z-1 |
16 | 2.5 | 4.7 | arthritis | 12 | spe B |
Median | 4.8 | 1.5 | |||
Range | 1.6-16.2 | 0.1-4.5 |