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  • Open Access

Value of skin testing children with a family history of food allergy before ingestion of suspect food allergens

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Allergy, Asthma & Clinical Immunology201410(Suppl 2):A29

Published: 18 December 2014


  • Family History
  • Food Allergy
  • Skin Testing
  • Anxiety Level
  • Post Testing


A family history of food allergy can cause anxiety in parents. This may prevent food introduction in their children. Current guidelines recommend skin testing only when there is a reaction to a food in that specific patient. When there is a family history of food allergy, parents frequently ask their physicians for food testing of their children prior to introduction of specific foods. We conducted this study to determine whether allergy skin testing reduces anxiety levels in parents thereby leading to food introduction.


The parents of 50 children with a family history of food allergy completed a Visual Analog Score (VAS) to estimate their anxiety to give their children the specific food of concern. Previously, the children had not eaten the food. The VAS scores were recorded pre- and post-skin testing on a scale from 0 to 10. The likelihood of food introduction pre- and post-skin testing was estimated.


The mean age of the children was 3.6 years; the majority were males (62%). Approximately 58% of patients’ parents, 38% siblings and 4% other relatives had food allergy. Most children (78%) had family history of a single food allergen and 60% had a family history of allergy to peanuts. All children tested negative for the food allergen of concern. Mean VAS was statistically different pre- and post-skin testing (pre VAS mean= 7.83 vs post VAS mean = 2.15; p=<0.0001). The likelihood of food introduction pre- and post testing was 4% and 92% respectively.


Skin testing reduces the anxiety of parents of children with a family history of food allergy prior to introduction of the food allergen of concern. The food is more likely to be introduced into the diet after negative skin testing. Although it did not occur in this study, there is a still a risk of false positive skin testing.

Authors’ Affiliations

Division of Clinical Immunology and Allergy, Western University, London, Canada
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
McGill University, Montreal, Canada
Division of Clinical Immunology and Allergy, McMaster University, Hamilton, Canada


© Dominic et al; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.