Objective/purpose
In asthma, CD4+T cells are selectively recruited into the bronchial mucosa. CD4+ T cells consist of different subsets that express lineage specific transcription factors and play different roles either in initiating and supporting the development of immune response, but also in orchestrating and regulating them. The aim of our study was to evaluate the effect of T cells-bronchial fibroblasts interaction on CD4+T cell phenotype.