Overall 114 children and their parents were included in this analysis. Of the 114 children, 47 were females (21 asthma) and 67 were boys (23 asthma). No significant relationship was seen between children diagnosed with asthma and having a parent with a PC30 ≤ 8 (OR 1.07; 95% CI 0.49-2.37) or both parents PC30 >8.
112 children [45 females (23 with PC20 ≤ 8) and 67 males (46 with PC20 ≤ 8)] fit the criteria for having a PC20 and participating parents. In children with a PC20 ≤ 8 there was no relationship between having one parent with PC30 ≤ 8 (OR 1.18; 95% CI .54-2.63) or both parents having a PC30 >8.
When we examined gender specific relationships, there was no association between fathers PC30 and having a son diagnosed with asthma (OR 1.32; 95% CI 0.5-3.5) or daughters with a diagnosis of asthma (OR 1.07; 95% CI 0.33-3.48). Similarly, there was no significant association between the father's PC30 and their child's PC20 being ≤ 8 mg/ml.
In moms with a PC30 ≤ 8 mg/ml there was no association with sons that had a PC20 ≤ 8 mg/ml (OR 1.0; 95% CI 0.51-2.0); However moms with a PC30 ≤ 8 were significantly more likely to have a daughter with a PC20 ≤ 8 (OR 3.56; 95% CI 1.55-8.21). In addition, there was a significant relationship between mom's PC30 being ≤ 8 and a daughter having physician diagnosed asthma (OR2.34; 95% CI 1.04-5.44). The relationship was in the same direction between maternal PC30 and a son's diagnosis of asthma, however this was not significant (OR 2.0; 95% CI 0.99-4.05).