NAA (7.8%) was less common than AA (22.4%).NAA vs. AA was 9.9%/20.8% in females, 6.2%/23.6% in males. Mean FEV1% predicted (87.8% vs. 87.3%) did not differ between the NAA's and AA's. Wheezing episodes in the last year (2.3 vs. 2.7 p = 0.426) and episodes of sleep disturbances due to wheeze (0.7 vs. 0.5 p = 0.280) were not significantly different. NAA's had slightly, but not significantly higher total cholesterol (4.0 mmol/L vs. 3.9 mmol/L), LDL (2.2 mmol/L vs. 2.0 mmol/L) and lower HDL (1.4 mmol/L vs. 1.49 mmol/L). For children with BMI >85%ile (n = 144), NAA's had higher mean cholesterol (p = 0.08). NAA's also had marginally higher systolic blood pressure (115.5 mmHg vs. 113 mmHg) but not statistically significant. Mean waist circumference (75.7 cm vs. 71.2 cm) and weight (54.6 kg vs. 50.7 kg) were higher in the NAA group but also not statistically significant. Early life tobacco exposure had an important influence on our subtypes. Interestingly, mothers of non-atopic asthmatics smoked fewer cigarettes/day in the first year of life (1.11 vs. 1.71 p = 0.025).