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Table 3 Risk factors for the development of drug allergy [15]

From: Drug allergy

• Patient-related factors:
• Age: young/middle-aged adults > infants/elderly
• Gender: Women > men
• Genetic polymorphisms
• Viral infections: HIV, herpes viruses
• Previous reaction to the drug
Drug-related factors:
• High molecular weight compounds and hapten-forming drugs are more immunogenic
• Route: topical > intravenous/intramuscular > oral
• Dose: frequent/prolonged > single dose
  1. HIV: human immunodeficiency virus