Table 1 Allergen-specific Immunotherapy: indications, contraindications and special considerations [5–7]
Indications: | • Patients with stinging insect (venom) hypersensitivity • Patients with allergic rhinitis/conjunctivitis and/or allergic asthma who have evidence of specific IgE antibodies to clinically relevant allergens; includes patients who: – Do not achieve control of symptoms with avoidance measures and pharmacotherapy – Do not want ongoing or long-term pharmacotherapy – Experience undesirable side effects with pharmacotherapy |
|---|---|
Contraindications: | • Patients on beta-blockers (relative contraindication with venoms) • Patients with uncontrolled or severe asthma • Significant co-morbid diseases such as cardiovascular disability |
Special considerations: | • Children < 6 years of age • Pregnancy • The elderly • Patients with malignancy, immunodeficiency and autoimmune diseases |