Table 1 Age at first symptoms and diagnosis, and delay in diagnosis by patient type
From: Hereditary angioedema with C1 inhibitor deficiency: delay in diagnosis in Europe
N | Median | Q1 | Q3 | Min | Max | Mean | Standard deviation | p-value | ||
|---|---|---|---|---|---|---|---|---|---|---|
Age at first symptoms (years) | Male | 61 | 13.0 | 6.0 | 20.0 | 1.3 | 60.0 | 15.9 | 12.53 | 0.199 |
Female | 92 | 11.5 | 5.0 | 18.0 | 0.2 | 77.0 | 13.6 | 12.15 | ||
HAE type I | 140 | 12.0 | 6.0 | 19.0 | 0.2 | 77.0 | 14.4 | 12.29 | 0.870 | |
HAE type II | 13 | 13.0 | 6.0 | 18.0 | 2.0 | 50.0 | 15.3 | 13.12 | ||
FH+ | 106 | 13.0 | 6.0 | 19.0 | 0.2 | 50.0 | 13.7 | 9.42 | 0.513 | |
FH- | 32 | 14.0 | 5.0 | 26.5 | 0.8 | 77.0 | 19.6 | 19.60 | ||
Total | 153 | 12.0 | 6.0 | 19.0 | 0.2 | 77.0 | 14.5 | 12.32 | ||
Age at diagnosis (years) | Male | 66 | 25.1 | 17.9 | 33.0 | 9.1 | 68.3 | 27.6 | 14.06 | 0.844 |
Female | 104 | 23.3 | 15.8 | 38.3 | 0.0 | 77.3 | 28.1 | 17.37 | ||
HAE type I | 157 | 22.1 | 16.1 | 36.0 | 0.0 | 77.3 | 27.3 | 15.87 | 0.080 | |
HAE type II | 13 | 31.8 | 24.2 | 43.5 | 3.3 | 74.2 | 34.9 | 18.18 | ||
FH+ | 121 | 24.4 | 16.2 | 35.2 | 0.0 | 74.2 | 26.9 | 14.96 | 0.509 | |
FH- | 33 | 22.3 | 17.1 | 45.0 | 3.8 | 77.3 | 30.5 | 19.10 | ||
Total | 170 | 24.3 | 16.9 | 36.2 | 0.0 | 77.3 | 27.9 | 16.13 | ||
Delay between first symptoms and diagnosis (years) | Male | 60 | 8.5 | 3.0 | 17.0 | 0.0 | 60.0 | 11.2 | 10.97 | 0.771 |
Female | 92 | 8.5 | 1.0 | 24.0 | 0.0 | 62.0 | 13.9 | 14.88 | ||
HAE type I | 139 | 8.0 | 2.0 | 20.0 | 0.0 | 62.0 | 12.2 | 13.35 | 0.051 | |
HAE type II | 13 | 21.0 | 7.0 | 30.0 | 0.0 | 42.0 | 19.6 | 13.80 | ||
FH+ | 106 | 8.5 | 2.0 | 21.0 | 0.0 | 57.0 | 12.5 | 12.94 | 0.476 | |
FH- | 31 | 6.0 | 1.0 | 20.0 | 0.0 | 62.0 | 10.8 | 13.38 | ||
Total | 152 | 8.5 | 2.0 | 21.0 | 0.0 | 62.0 | 12.9 | 13.5 |