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Table 2 Primary effects of glucocorticoids (GCs)[1]

From: A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy

Anti-inflammatory:

Inhibit inflammation by blocking the action of inflammatory mediators (transrepression), or by inducing anti-inflammatory mediators (transactivation)

Immunosuppressive:

Suppress delayed hypersensitivity reactions by directly affecting T-lymphocytes

Anti-proliferative:

Inhibition of DNA synthesis and epidermal cell turnover

Vasoconstrictive:

Inhibit the action of histamine and other vasoconstrictive mediators

  1. DNA deoxyribonucleic acid.
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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